摘要
辐照灭菌具有穿透力强、无明显温度升高、无有害物质残留和剂量容易控制等优点 ,被广泛用于同种骨移植物的灭菌。辐照灭菌剂量应做到最优化选择 ,既能满足对同种骨的有效灭菌 ,又能在降低同种骨免疫原性的同时最大程度保持骨的生物性能 ,确保同种骨移植的安全有效。国际原子能机构 ( IAEA)自 1986年起在发展中国家推广组织移植物辐照灭菌技术 ,中国辐射防护研究院在 IAEA的资助下于 1988年建立组织库 ,后改建为山西省医用组织库 ,向临床提供辐照灭菌同种骨 ,并致力于骨辐照技术在国内的推广。
With prominent features of high penetration,no temperature increases, no harm residues and easy dose control,radiation sterilization technology is widely used in the sterilization of bone allografts. During the radiation sterilization of bone allografts, the irradiation dose should be optimized to ensure sterilization of grafts and preservation of biological properties of bone. The immunogenicity of allografts is decreased by irradiation. IAEA devoted great efforts to generalinzation of the radiation sterilization of tissue allografts in developing countries since 1986. Tissue Bank of China Institute for Radiation Protection (CIRP) was initially established in 1988 with the support of IAEA, afterwards restructured into Shanxi Provincial Tissue Bank (SPTB). The SPTB,as the first manufacturer of the irradiated bone allografts in the country,was granted production license by the State Food and Drug Administration of China.The SPTB sponsored IAEA/RCA Training Courses, National Symposium on Bone Grafting, and National Training Course on Bone Banking. Technique of radiation sterilization for bone grafts has become popularized in China after these activities.
出处
《辐射防护通讯》
2003年第5期16-18,共3页
Radiation Protection Bulletin
