期刊文献+

硒缺乏与甲状腺疾病 被引量:9

下载PDF
导出
摘要 硒在甲状腺激素的合成、活化、代谢过程及甲状腺抗氧化系统和免疫系统中发挥重要作用。甲状腺滤泡上皮细胞表达众多功能性硒蛋白(含硒基半胱氨酸的酶),如:谷胱甘肽过氧化物酶、脱碘酶、硫氧还原蛋白还原酶(TR)及硒蛋白P。硒缺乏与许多甲状腺疾病如甲状腺肿、亚临床克汀病、自身免疫性甲状腺炎、低T4综合征、甲状腺癌等密切相关。补硒可能会给这些疾病的治疗开辟一条新的途径。
作者 刘莉 朱本章
出处 《国外医学(内分泌学分册)》 2003年第6期386-388,共3页 Foreign Medical Sciences(Section of Endocrinology)
  • 相关文献

参考文献9

  • 1Zagrodzki P, Nicol F, McCoy M A, et al. Iodine deficiency in cattle: compensatory changes in thyroidal selenoenzymes[J]. Res Vet Sci, 1998, 64:209-211.
  • 2Zagrodzki P, Szmigiel H, Ratajczak R, et al. The role of selenium in iodine metabolism in children with goiter [ J ].Enviro Health Perspect, 2000, 108 : 67-71.
  • 3Pizzulli A, Ranjbar A. Selenium deficiency and hypothyroidism : a new etiology in the differential diagnosis of hypothyroidism in children [J]. Biol Trace Elem Res, 2000,77 : 199-208.
  • 4Giray B, Hincal F, Tezic T, et al. Status of selenium and antioxidant enzymes of goitrous children is lower than healthy controls and nongoitrous children with high iodine deficiency[J]. Biol Trace Elem Res, 2001, 82:35-52.
  • 5Gartner R, Gasnier B C, Dietrich J W, et al. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations [ J ] . J Clin Endocrinol Metab, 2002, 87 : 1687-1691.
  • 6Schilling J U, Zimmermann T, Albrecht S, et al. Low T3 syndrome in multiple trauma patients-a phenomenon or important pathogenetic factor? [ J]. Med Klin, 1999, 94( Suppl 3) : 66-69.
  • 7Berger M M, Reymond M J, Shenkin A, et al. Influence of selenium supplements on the post-traumatic alterations of the thyroid axis: a placebo-controlled trial[J]. Intensive Care Med, 2001, 27:91-100.
  • 8Burk R F. Selenium : recent clinical advances [ J ]. Nutrition, 2001, 17:162-166.
  • 9Kucharzewski M, Braziewicz J, Majewska U, et al. Concentration of selenium in the whole blood and the thyroid tissue of patients with various thyroid diseases [J]. Biol Trace Elem Res, 2002, 88:25-30.

同被引文献108

引证文献9

二级引证文献67

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部