摘要
目的探讨饮酒与脂肪肝的关系 ,以及酒精性脂肪肝病因的量化标准。方法将连续性体检人群分成非饮酒组、白酒组 (按日均饮酒量下分 <5 0g、5 0～ 1 0 0g及 >1 0 0g白酒组 )和啤酒组 (按日均饮酒量下分 <2 5 0mL、2 5 0～ 5 0 0mL及 >5 0 0mL啤酒组 ) ,对各组脂肪肝检出率及脂肪肝患者饮酒至发病时间进行流行病学调查。结果 5 0～ 1 0 0g及 >1 0 0g白酒组 ,2 5 0～ 5 0 0mL及>5 0 0mL啤酒组脂肪肝检出率分别为 4 3.6 % ,5 0 .0 % ,6 4.5 % ,6 6 .7% ,较非饮酒组的 2 5 .0 %明显增高 (P <0 .0 1 )。各组中脂肪肝患者饮酒时间显著高于同酒量非脂肪肝者 (P <0 .0 1 )。以日均饮白酒 80g、时间 9.0年 ,或日均饮啤酒 4 0 0mL、时间 5 .0年作为各自酒精性脂肪肝病因量化标准 ,分别具有 82 .6 %、88.6 %敏感性 ,72 .2 %、78.3%特异性。结论饮酒与脂肪肝的发生具有量效和时效关系 ,日均饮白酒 80g、时间 9.0年 ,以及日均饮啤酒 4 0 0mL、时间 5 .0年为其各自酒精性脂肪肝较好的病因量化诊断标准。
Objevtive To study the relation between drinking alcohol and fatty livr and the rating diagnostic standard of etidogy of alcoholic fatty liver. Methods 615 men came to the hospital for physical examination were divided into non alcohol group, liquor groups (includng <50 g,50～100 g, and >100 g three daily drinking amount groups) and beer groups (including <250 mL,250～500 mL,and >500 mL three daily drinking amount groups). The incidence of fatty liver, and drinking duration of patients with fatty liver were investigated. Results The detection rates of fatty liver in 50～100 g and >100 g liquor group, and in 250～500 mL and>500 mL beer group (43.6%,50.0%,64.5%,66.7%,respectively) were higher than that in non alcohol group (25.0%,P<0.01). The patients with fatty liver had longer drinking duration than those without fatty liver but with the same drinking amount (P<0.01).The results also indicated that 80 g of liguor per day with 9-year drinking duration, and 400 mL of beer per day with 6-year drinking duration may be the rating diagnostic standard of fatty liver etiology. The sensitivity and specifivity of both were 82.6%,88.6% and 72.2%, 78.3% respectively. Conclusion There were dose-effect and time-effect relationship of the occurrence of alcoholic fatty liver. 80 g of daily drinking amount with 9-year drinking duration for liquor, and 400 ml with 6-year for beer may be considered as the rating diagnostic standard.
出处
《解放军预防医学杂志》
CAS
北大核心
2003年第5期327-330,共4页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
脂肪肝
酒精性
非酒精性
白酒
啤酒
fatty liver
alcoholic
non alcoholic
liquor
beer
