摘要
目的:分析药源性过敏性休克的基本情况及其发生原因。方法:对1991～1999年国内24种杂志进行专题检索。结果:共收集到487例药源性过敏性休克病例,由109种药物引起,发生率最高的药物为抗生素。死亡69例,65％患者(317例)在用药后5min内发生。文中还对药物性休克发生原因进行了讨论。结论:本文供临床参考,以减少药源性休克发生和死亡。
Objective: To understand the aspects of drug-induced allergic shock and its causes. Methods: The cases with drug-induced allergic shock were retrieved from 24 journals in Chinese of 1991-1999. Results: 487 cases were collected and the allergic shock was caused by 109 drugs, mostly by antibiotics. It came rapidly with 69 deaths, occuring within 5 minutes after drug administration in 65% of the patients (317 cases) . The reasons of the shock were discussed in this paper. Conclusion: The work here is for clinical reference in order to reduce its occurrence and the resulting death.
出处
《药物不良反应杂志》
2000年第4期228-232,共5页
Adverse Drug Reactions Journal
