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神经胶质瘤的基因治疗策略现状和未来 被引量:2

Strategies of glioma gene therapy and its prospect
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摘要 神经胶质瘤基因治疗按策略可分为以杀伤肿瘤细胞细胞为目的、以纠正肿瘤细胞的生物学性状为目的和以破坏肿瘤血管为目的。RNA干扰技术和神经干细胞技术突破对胶质瘤的基因治疗策略产生强烈冲击。本文就神经胶质瘤基因治疗研究进展做简要介绍,并探讨治疗策略的未来发展方向。 Strategies of Neuroglioma gene therapy are based on 3 curative aims: to kill tumor cells, to redress biological character of tumor cells and to destruct tumor vessels. Breakthroughs in RNA interference and neural stem cell technology have produced fierce impact on the therapies. In this paper, the author has summarized the progress of neuroglioma gene therapy strategies and made a prospect upon the development.
作者 徐如祥
出处 《中华神经医学杂志》 CAS CSCD 2003年第6期401-403,共3页 Chinese Journal of Neuromedicine
关键词 神经胶质瘤 基因 治疗 神经干细胞 肿瘤细胞 glioma gene therapy neural stem cell RNA interference
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