摘要
2型糖尿病的根本病因是胰岛素抵抗和B细胞功能损害。传统的治疗方法不能针对糖尿病病因 ,因而无法实现血糖的长期控制。罗格列酮则能显著降低胰岛素抵抗并改善B细胞功能 ,从而持久稳定地控制糖尿病。
The basic cause of type 2 diabetes is the insulin resistance and the beta cells dysfunctional. Rosiglitazone can improve insulin sensitivity, protect the function of pancreatic B cells and steadily control the blood glucose. This article explains the mechanism and clinical efficacy of rosiglitazone in treating type 2 diabetes mellitus.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2003年第12期751-753,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
降血糖药
罗格列酮
糖尿病
非胰岛素依赖型
药物评价
药理学
hypoglycemic agents
rosiglitazone
diabetes mellitus, non insulin dependent
drug evaluation
pharmacology