摘要
目前越来越多的研究成果表明被誉为人类"第二基因组"的肠道菌群能够影响糖脂代谢,进而调节相应疾病。本文就肠道菌群的分布、种类、影响因素进行大体介绍,主要对肠道菌群与糖脂代谢疾病联系和肠道菌群调节糖脂代谢过程中可能存在的作用机理进行综述,希望能够对糖脂代谢疾病的临床诊治带来裨益,为在此领域上的研究者提供参考价值。
Accumulating literatures indicate that intestinal microflora,known as the second human genome,can affect glycolipid metabolism,and then regulate the corresponding diseases.In this review,we introduce the distribution,species and influencing factors of intestinal microflora.We mainly address the relationship between intestinal microflora and glycolipid metabolic diseases,and the mechanism how intestinal microflora regulates the glycolipid metabolism.Moreover,the potential use of glycolipid metabolism for clinical diagnosis and treatment of diseases is also discussed.
作者
杨俊
王健宇
陈茏
周飞
曾哲灵
文学方
YANG Jun;WANG Jian-Yu;CHEN Long;ZHOU Fei;ZENG Zhe-Ling;WEN Xue-Fang(State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang,Jiangxi330047,China;Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation,Nanchang University,Nanchang,Jiangxi330031,China;School of Food Science and Technology,Nanchang University,Nanchang,Jiangxi330031,China;School of Resource Environmental and Chemical Engineering,Nanchang University,Nanchang,Jiangxi330031,China)
出处
《微生物学通报》
CAS
CSCD
北大核心
2019年第5期1146-1154,共9页
Microbiology China
基金
国家国际科技合作专项项目(2011DFA32770)
江西省国际科技合作项目(20112BDH80004
20123BDH80011)
食品科学及技术国家重点实验室目标导向项目(SKLF-ZZA-201303)~~
关键词
肠道菌群
糖脂代谢
糖脂代谢疾病
Gut microflora
Glycolipid metabolic
Glycolipid metabolic disease
