摘要
目的 探讨P波离散度 (Pd)能否预测高血压病患者伴发的阵发性心房颤动的发生。方法 观察 46例有阵发性心房颤动病史的高血压病患者 (Ⅰ组 :平均年龄 62岁 )的最大P波时限(Pmax)、最小P波时限 (Pmin)、Pd、左房内径 (LAD)和左室射血分数 (LVEF) ,并与无阵发性心房颤动病史的 48例高血压病患者 (Ⅱ组 :平均年龄 58岁 )比较。结果 Pmax :Ⅰ组非常显著高于Ⅱ组[(12 4 92± 14 0 6)ms比 (112 52± 11 68)ms,P <0 0 0 1] ;Pd :Ⅰ组非常显著高于Ⅱ组 [(50 89±13 72 )ms比 (3 7 82± 9 0 1)ms,P <0 0 0 1] ;LVEF :Ⅰ组显著低于Ⅱ组 [(62 0 9± 6 3 2 ) %比(65 14± 5 89) % ,P <0 0 5]。Pmin、LAD两组差别无统计学意义。单因素回归分析显示 :Pmax、Pd、LVEF均是阵发性心房颤动的预测因子。多因素回归分析显示仅Pd是阵发性心房颤动的独立预测因子。结论 Pmax、LVEF和Pd均可能预测高血压病患者伴发的阵发性心房颤动的发生 。
Objective To explore whether patients with essential hypertension at risk of paroxysmal atrial fibrillation (PAF) can be identified in sinus rhythm by measurements of P wave dispersion Methods We measured the maximum P wave duration(Pmax), the minimum P wave duration(Pmin), and P wave dispersion (Pd=Pmax-Pmin) from the 12-leads surface electrocardiogram of 46 essential hypertensive patients with history of PAF (group Ⅰ, mean age 62) and 48 essential hypertensive patients without history of PAF (group Ⅱ, mean age 58) Left atrial dimension (LAD) and left ventricular ejection fraction (LVEF) were measured by echocardiography Results Pmax and Pd were found to be significantly higher in group Ⅰ than group Ⅱ (Pmax, 124 92 ±14 06 ms vs 112 52±11 68 ms,P < 0 001; Pd, 50 89±13 72 ms vs 37 82±9 01 ms, P <0 001) LVEF was significantly lower in group I than group Ⅱ (62 09± 6 32% vs 65 14±5 89 %,P< 0 05) In univariate analysis, Pmax, Pd and LVEF were significant predictors of PAF, whereas only Pd remained a significant independent predictor of PAF in the multivariate analysis Conclusions Pmax Pd and LVEF could be used for the prediction of essential hypertensive patients at risk of developing PAF Pd remained significant independent predictor of PAF in the multivariate analysis
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2003年第10期739-741,共3页
Chinese Journal of Cardiology
