摘要
建立反相高效液相色谱法测定利血平片剂的含量。采用HypersilC18柱 ,甲醇 -水 -冰醋酸 (70∶30∶0 8)为流动相 ,流速 1 0ml·min-1,检测波长 2 6 8nm。利血平在 4～ 36 μg·ml-1范围内有良好的线性关系(r=0 9999) ,平均回收率为 10 0 4 % (n =6 )。本法快速、简便、准确。
An RP-HPLC method was developed for the content determination of Reserpine Tablet. Hypersil C18 column was used with the mobile phase of methanol-water-acetic acid (70∶30∶0.8) at a flow rate of 1.0ml min-1. The detection wavelength was 268nm. Resperpine presented a good linear relation within a range of 4～36μg·min -1 (r=0.9999), the average recovery was 100.4% (n=6). This method was rapid, simple and accurate.
出处
《中国药事》
CAS
2003年第12期758-759,共2页
Chinese Pharmaceutical Affairs
