摘要
应用放射免疫分析法检测656例恶性肿瘤患者血清中 CEA 含量,结果显示32.3%患者均高于正常,以胆管癌灵敏度最高(66.7%)。对109例结、直肠癌术后患者术后6周至6年随访中,有22例 CEA 增高,结果证实已向肝、肺和盆腔等部位复发转移,提示 CEA 测定可作为诊断恶性肿瘤和监测复发的一项指标。180例原发性肝癌患者联合测定血清 CEA 和 AFP,结果显示58例 CEA 阳性肝癌患者的 AFP 灵敏度达34.5%;122例 CEA 阴性肝癌患者的 AFP 灵敏度达82.8%,认为 CEA和 AFP 联合测定可早期诊断原发性肝癌,提高灵敏度。
The radioimmunoassay method has been used to measure CEA content in serum coming from 656patients with malignant tumor.The results showed that CEA values in 32.3% patients are higher than that in normal with the highest value in patients with bile duct cancer(66.7%).Following up 109patients with colon and rectum cancer from 6 weeks to 6 years after operation it was found that in 22patients who had recurrence CEA values increased.It has been proved that cancer cells metastasized toliver,lung,pelvic cavity etc and recurrence oeeured there.This fact implies that CEA measurementcan be used as an index for diagnosing malignant tumor and monitoring its recurrence.The resultsfrom a combining measurement of CEA and AFP values in serums of 180 patients with primary livercarcinoma have shown that the AFP sensitivities for 58 patients with CEA positive hepatic cancer and122 with CEA negative hepatic cancer were 34. 5% and 82. 8% respectively.We assume that bymeans of the combining measurement primary carcinoma of the liver can be early diagnosed.
出处
《苏州医学院学报》
1992年第2期127-128,147,共3页
Acta Academiae Medicinae Suzhou
关键词
癌胚抗原
放射免疫测定
癌
carcinoembryonic antigen
radioimmunoassay
malignant tumor
