摘要
目的:探究颅内动脉瘤夹闭术术中动脉瘤破裂患者预后情况及相关危险因素。方法:分析2012-01~2014-12我院收治的71例行颅内动脉瘤夹闭术患者的临床资料,根据术中颅内动脉瘤是否发生破裂分为破裂组(37例)和非破裂组(34例)。采用mRS评分评估术中破裂患者6个月内预后情况;采用Logistic回归分析相关危险因素。结果:两组术后6个月mRS评分比较无明显差异(P>0.05);破裂组患者术后6个月mRS评分有效率明显低于非破裂组,差异具有统计学意义(P<0.05);术中动脉瘤破裂患者预后情况与年龄、术前Hunt-Hess分级、肿瘤直径、肿瘤破裂点相关,均有统计学差异(P<0.05或P<0.01);Logistic多因素回归分析发现,年龄越大、术前Hunt-Hess分级越严重、肿瘤颈部破裂是影响术中动脉瘤破裂患者预后不良的危险因素。结论:明确影响动脉瘤破裂患者预后不良的危险因素,有助于采取相应的措施改善患者预后。
Objective:To investigate the prognosis and risk factors of intraoperative aneurysm rupture patients with intracranial aneurysm clipping.Methods:Seventy-one patients who underwent intracranial aneurysm clipping in our hospital from January 2012 to December 2014 were divided into the rupture group(37cases)and no-rupture group(34cases)according to whether there was intraoperative intracranial aneurysms rupture.Their clinical data were analysed.The prognosis within six months of intraoperative fracture patients were evaluated by mRS score,and the related risk factors were analyzed by Logistic regression.Results:mRS score within 6months in the two groups had no significant difference(P>0.05).The rupture group had a statistically significant lower mRS score than that of the non-rupture group(P<0.05).As to the intraoperative aneurysm rupture patients,age,preoperative Hunt- Hess classification,tumor diameter and tumor rupture point had statistically significant difference in patients with favorable prognosis and poor prognosis(P<0.05 or P<0.01).The Logistic multifactor regression analysis showed that increase of age,more serious of preoperative Hunt-Hess classification and tumor neck rupture were risk factors of poor prognosis.Conclusion:Understanding the risk factors causing poor prognosis for intraoperative aneurysm rupture patients is helpful to take appropriate measures to improve the outcome.
出处
《西北国防医学杂志》
CAS
2016年第8期516-519,共4页
Medical Journal of National Defending Forces in Northwest China
关键词
颅内动脉瘤夹闭术
破裂
预后
危险因素
intracranial aneurysm clipping
rupture
prognosis
risk factors
