摘要
目的:比较厄贝沙坦与贝那普利对高血压患者室性心律失常的影响。方法:2010年1月-2013年9月收治高血压合并室性心律失常患者80例,按照随机数字表法分为治疗组和对照组,各40例,治疗组给予厄贝沙坦进行治疗,对照组给予贝那普利,比较两种药物对高血压合并室性心律失常患者血压及室性心律失常发生情况的影响。结果:治疗后,两组患者的收缩压和舒张压均显著低于治疗前,差异均有统计学意义(P<0.05)。但是治疗后两组的收缩压、舒张压差异无统计学意义(P>0.05)。结果表明,在治疗高血压合并室性心律失常的患者时厄贝沙坦与贝那普利的降压效果相似。结论:厄贝沙坦治疗高血压患者室性心律失常,不仅能够有效控制血压,而且能够降低室性心律失常的发生,不良反应少,应该在临床治疗中广泛推广。
Objective:To compare the effects of irbesartan and benazepril in the treatment of hypertensive patients with ventricular arrhythmias.Methods:80 hypertension patients complicated with ventricular arrhythmia were selected from January2010 to September 2013.They were randomly divided into the treatment group and the control group with 40 cases in each.Patients in two groups were treated with irbesartan and benazepril respectively,we then compared the difference between two kinds of drugs in the incidence of blood pressure and ventricular arrhythmia among hypertension patients with ventricular arrhythmias.Results:After treatment,systolic and diastolic blood pressure in two groups both were significantly lower than that before the treatment,and the differences were statistically significant(P<0.05).But the differences in systolic pressure and diastolic pressure after treatment were no statistically significant between two groups(P>0.05).This showed that the hypotensive effect of irbesartan and benazepril was similar in hypertensive patients with ventricular arrhythmias.Conclusion:Irbesartan applied in the treatment of hypertensive patients with ventricular arrhythmias not only can control the blood pressure effectively,but also can effectively reduce the occurrence of ventricular arrhythmia,and less adverse reaction,so it is worthy of promotion.
