摘要
目的:ICU重度颅脑损伤患者肺部感染的临床观察以及疗效分析。方法:2010年6月-2013年9月收治重度脑颅损伤并肺部感染患者88例,随机分为对照组和观察组,每组44例,对照组采用头孢米诺钠进行静滴治疗,观察组前期也是用头孢米诺钠进行静滴,后改为头孢唑肟钠进行静滴,观察两组的病情变化以及细菌转阴率。结果:观察组治愈率95.45%,对照组治愈率72.73%,观察组疗效明显优于对照组,差异具有统计学意义(P<0.05);观察组细菌转阴率100%,明显高于对照组(P<0.05)。结论:对于ICU重度颅脑损伤并肺部感染患者,头孢米诺钠与头孢唑肟钠联合治疗具有较好的疗效,能有效改善患者病情,值得临床推广应用。
Objective:To explore the clinical observation and curative effect analysis of pulmonary infection in patients with severe craniocerebral injury in ICU.Methods:88 severe craniocerebral injury patients with pulmonary infection were selected from June 2010 to September 2013.They were randomly divided into the control group and the observation group with 44 cases in each.The control group was treated with cefminox sodium intravenous injection.The observation group was treated with cefminox sodium intravenous injection at the early stage,later change to ceftizoxime sodium intravenous injection.The condition changes and bacterial negative conversion rates of two groups were observed.Results:The cure rate of the observation group was 95.45%;the cure rate of the control group was 72.73%;the difference was statistically significant(P<0.05).The bacterial negative conversion rate of the observation group was 100%,which was significantly higher than that of the control group(P<0.05).Conclusion:For ICU severe craniocerebral injury patients with pulmonary infection,cefminox sodium and ceftizoxime sodium combined treatment has a better curative effect.It can effectively improve the condition of the patients.It is worthy of clinical strong application.
关键词
ICU
颅脑损伤
肺部感染
疗效
Intensive Care Unit
Craniocerebral injury
Pulmonary infection
Curative effect
