摘要
目的:探讨血清CA125检测在子宫内膜癌诊断和病情判断中的临床价值,为临床诊断提供指导。方法:2013年6月-2014年6月收治子宫内膜癌疑似患者112例,随机分为观察组和对照组,观察组于术前行血清CA125及血清HE4检测;对照组仅行血清HE4检测。以检测结果为依据对患者的疾病及病情进行诊断。根据术中病理诊断结果对检测结果进行评价,并进行组间比较。结果:观察组敏感性优于对照组,差异有统计学意义(P<0.05);观察组特异性88.6%低于对照组,但差异无统计学意义(P>0.05);观察组检测依从性94.6%略低于对照组的96.4%,差异无统计学意义(P>0.05)。结论:血清CA125检测在子宫内膜癌的辅助诊断和病情判断中能够在确保诊断特异性和依从性的基础上,提升检测的敏感性,具有重要的临床价值。
Objective:To explore the clinical value of serum CA125 detection in the diagnosis and prognosis of endometrial carcinoma,to provide guidance for clinical diagnosis.Methods:112 patients with suspected endometrial cancer were selected from June 2013 to June 2014.They were randomly divided into the observation and the control group.Before operation,the observation group was given serum CA125 and serum HE4 detection;the control group was given the detection of serum HE4.According to the test results,the disease of patients was diagnosed.According to the result of pathological diagnosis in operation,we evaluated the results,and made comparison between groups.Results:The sensitivity of 58.3% in the observation group was better than the control group,and the difference was statistically significant(P＜0.05);the specificity of 88.6% in the observation group was lower than that of control group,but there was no significant difference(P＞0.05);in the observation group,the detection of compliance was 94.6%,which was lower than 96.4% in the control group,and there was no significant difference(P＞0.05).Conclusion:Detection of serum CA125 for endometrial cancer assistant diagnosis and condition judgment can improve the detection sensitivity,on the basis of ensuring the basic diagnostic specificity and compliance,and it had important clinical value.
出处
《中国社区医师》
2015年第12期122-123,共2页
Chinese Community Doctors
关键词
血清CA125检测
子宫内膜癌
病情判断
临床价值
Detection of serum CA125
Endometrial carcinoma
Condition judgement
Clinical value
