摘要
目的:探讨前列地尔治疗对糖尿病肾病的治疗效果。方法:收治糖尿病肾脏病患者84例,将其分为前列地尔治疗组(A组)43例,对照组(B组)41例,两组均给予糖尿病饮食、控制血糖、稳定血压、降血脂、抗凝、改善微循环等对症基础治疗。结果:A组:24 h尿蛋白定量增加31例,稳定9例,减少3例;e GFR稳定8例,下降35例,其中发生肾衰竭2例。B组:24 h尿蛋白定量增加38例,稳定3例;e GFR稳定4例,下降37例,其中5例发生肾衰竭。结论:前列地尔的规范化使用可有效缓解糖尿病肾病的发展。
Objective:To investigate the effect of alprostadil in the treatment of diabetic nephropathy.Methods:84 patients with diabetic kidney disease were selected.They were divided into the alprostadil treatment group(group A) with 43 cases,and the control group(group B) with 41 cases.All of the patients in the two groups were given symptomatic treatment,including diabetic diet,controlling blood glucose,stable blood pressure,hypolipidemic,anticoagulant,improve microcirculation etc.Results:Group A:There 31 cases were increased in urinary protein quantitative during 24 h,and 9 cases were stable,3 cases were decreased;and 8 cases with stable EGFR,35 cases were reduced,in which there were 2 cases had renal failure.Group B:There 38 cases were increased in urinary protein quantitative during 24 h,and 5 cases were stable;and 4 cases with stable EGFR,37 cases were reduced,in which there were 5 cases had renal failure.Conclusion:Standardized use of alprostadil can alleviate the development of diabetic kidney disease effectively.
出处
《中国社区医师》
2015年第23期35-35,37,共2页
Chinese Community Doctors
关键词
糖尿病肾病
前列地尔
肾损害
蛋白尿
Diabetic nephropathy
Alprostadil
Renal damage
Proteinuria
