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甲巯咪唑联合左甲状腺素治疗儿童甲状腺功能亢进症的临床效果观察 被引量:8

The clinical effect of methimazole combined with levothyroxine in the treatment of hyperthyroidism in children
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摘要 目的:探讨甲巯咪唑联合左甲状腺素治疗儿童甲状腺功能亢进症的临床疗效。方法:收治甲状腺功能亢进症患儿120例,随机分成观察组和对照组各60例,对照组采用甲巯咪唑和他巴唑治疗,观察组在对照组基础上加用左甲状腺素治疗,比较两组的治疗效果。结果:治疗2个月和治疗结束后,两组的TSH、FT3、FT4、甲状腺体积与治疗前比较,差异有统计学意义(P<0.05),且观察组的TSH、甲状腺体积与对照组比较,差异有统计学意义(P<0.05)。结论:甲巯咪唑联合左甲状腺素治疗儿童甲状腺功能亢进症不良反应少,临床疗效显著。 Objective:To explore the clinical effect of methimazole combined with levothyroxine in the treatment of hyperthyroidism in children.Methods:120 children with hyperthyroidism were selected,they were randomly divided into the observation group and the control group with 60 cases in each,the control group was treated with methimazole combined with tapazole,the observation group was treated with levothyroxine on the basis of the control group,we compared the treatment effect of the two groups.Results:At treatment for 2 months and after treatment,compared with before treatment,the differences in TSH,FT4, FT3 and thyroid volume were statistically significant(P<0.05),and the differences in TSH and thyroid volume between the observation group and the control group were statistically significant(P<0.05).Conclusion:The clinical effect of methimazole combined with levothyroxine in the treatment of hyperthyroidism in children was significant,and adverse reactions were few.
作者 杜牧
出处 《中国社区医师》 2015年第33期46-46,48,共2页 Chinese Community Doctors
关键词 儿童甲状腺功能亢进症 甲巯咪唑 左甲状腺素 Hyperthyroidism in children Methimazole Levothyroxine
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