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妊娠滋养细胞肿瘤多药耐药机制的研究进展 被引量：1

Progress in study on the mechanism of multiple drug resistance in the treatment of gestational trophoblastic tumor
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摘要 妊娠滋养细胞肿瘤是一类恶性程度较高的妇科疾病 ,由于化疗方案的改进 ,其预后已有了很大改善。但近年来肿瘤多药耐药性的产生和某些临床因素 ,成为化疗失败的主要原因。该文就其多药耐药机制的研究现状作一综述 ,有助于临床选择合适的化疗方案 ,提高肿瘤患者的生存率。 Gestational trophoblastic tumor is a kind of highly malignant gynecological tumor. Its prognosis has been improved because of the improvement in chemotherapy program. However, recently, the increased multiple drug resistance and some clinical factors have become the main cause of chemotherapy failure. In this paper, we summarized the status of study on the mechanism of MDR, so as to help gynecologists to select suitable chemotherapy for the patients.
作者 傅晓华 石一复
机构地区 浙江大学医学院附属妇产科医院
出处 《国外医学（妇幼保健分册）》 2003年第6期387-390,共4页 Foreign Medical Sciences (Section of Maternal and Child Health)
关键词 妊娠滋养细胞肿瘤 多药耐药 gestational trophoblastic tumor multiple drug resistance
分类号 R737.3 [医药卫生—肿瘤]
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参考文献16

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同被引文献16

  • 1崔竹梅,杨秀玉,向阳,宋鸿钊,邵丽娜,李大兵.足月产后绒癌误诊分析[J].中国妇产科临床杂志,2001,2(1):22-24. 被引量：8
  • 2万希润,向阳,杨秀玉,吴郁,刘宁,陈玲,董若凡.FAEV化疗方案治疗高危型耐药性妊娠滋养细胞肿瘤的疗效分析[J].中华妇产科杂志,2006,41(2):88-90. 被引量：11
  • 3雷呈志,向阳,万希润,杨隽钧,崔全才,冯凤芝,杨秀玉.足月产后绒毛膜癌患者的临床特征与预后分析[J].中华妇产科杂志,2006,41(11):752-755. 被引量：7
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  • 5Smith HO, Kohorn E, Cole LA. Choriocarcinoma and gestational trophoblastic disease. Obstet Gynecol Clin North Am,2005;32(4) :661-684.
  • 6向阳.宋鸿钊滋养细胞肿瘤学.第3版.北京:人民卫生出版社,2011:84—86.
  • 7Ma v, Xiang Y, Wan XR, et al. The prognostic analysis of 123 postpartum choriocarcinoma cases. Int J Gynecol Cancer, 2008;18(5) :1097-110l.
  • 8Powles T, Young A, Sanitt A, et al , The significance of the time interval between antecedent pregnancy and diagnosis of high-risk gestational trophoblastic tumours. Br J Cancer, 2006; 95(9) :1145-1147.
  • 9Bianconi Ml , Otero S, Moscheni 0, et al . Gestational trophoblastic disease: a 21-year review of the clinical experience at an Argentinean public hospital. J Reprod Med , 2012;57(7-8) :341-349.
  • 10Cagayan MS. High-risk metastatic gestational trophoblastic neoplasia. Primary management with EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine) chemotherapy. J Reprod Med,2012;57(5-6) :231- 236.

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国外医学（妇幼保健分册）
2003年 第6期

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