静脉联合局部应用氨甲环酸在膝关节滑膜炎关节镜手术中的临床疗效分析被引量：2

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摘要目的通过探讨不同途径应用氨甲环酸对膝关节滑膜炎关节镜手术后出血及关节功能恢复的影响。方法选取2017年6月至2018年6月重庆三峡中心医院骨关节科收治的拟行膝关节镜手术的单纯滑膜炎患者共75例,将患者随机分为三组,每组25例。A组静点联合局部TXA;B组局部TXA;C组对照组。随访记录各组引流量、记录术前、术后1周及4周后Lysholm膝关节功能评分,随访术后深静脉血栓(DVT)、肺栓塞(PE)发生率、感染、血管神经损伤、药物不良反应发生。结果术后引流量A组较其他两组减少显著,B组则较C组减少显著,差异均有统计学意义(P <0.05)。术前Lysholm评分三组患者差异并无显著统计学意义(P> 0.05),术后1周Lysholm评分A组高于B组及C组对照组,B组高于C组对照组(P <0.05),术后4周3组Lysholm评分差异无统计学意义(P> 0.05)。3组患者随访期间均无DVT、PE及感染、血管神经损伤、药物不良反应发生。结论手术切皮前5 min使用10 mg/kg TXA静脉点滴联合缝皮后关节腔内注入20 mLTXA能有效减少膝关节镜手术术后出血,促进术后关节功能早期恢复,且联合用药无相关并发症增高风险。

作者杨勇吉明

机构地区重庆三峡中心医院骨关节病区

出处《现代医学与健康研究电子杂志》 2019年第6期8-9,11,共3页 Modern Medicine and Health Research

关键词膝关节镜滑膜切除术氨甲环酸联合用药引流量关节功能

分类号 R687.4 [医药卫生—骨科学]

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