摘要
目的 :评价磷酸钙骨水泥 (calciumphosphatecement ,CPC)强化和修复椎弓根螺钉的生物力学效果。方法 :6具新鲜老人骨质疏松的脊柱标本 ,从T11～L4 共 36个椎体 ,随机选取其中 32个 ,分为 4组 ,每组 8个。A组 :随机选择一侧椎弓根放置直径为 6 .5mm的椎弓根螺钉 ,另一侧以直径为 3.5mm的钻头导孔。向两侧椎弓根孔道注入配制好的磷酸钙骨水泥 (CPC) 3～ 5ml ,体温下 ( 37℃ )放置 2 4h后 ,再行前述拔出实验。B组 :应用PMMA进行修复和强化 ,作为对照 ,操作方法同A组。C组 :植入椎弓根螺钉 ,添加或不添加CPC ,进行周期抗屈实验。D组 :相同方法 ,应用PMMA作为对照。结果 :CPC骨水泥强化组和修复组拔出力明显高于对照组 ,差异有显著性意义 (P <0 .0 5)。结论 :在植入椎弓根螺钉时添加具有生物活性的磷酸钙 (CPC)
Objective:To evaluate pedicle screw fixation strength following augmentation and restoration with calcium phosphate cement (CPC).Methods:A total of thirty two fresh thoracolumbar vertebrae of six adult cadavers were employed in this experiment.The specimens were randomly divided into four groups,each group included eight vertebrae(T 11 ～L 4).Group A:self designed screws of 6.5mm diameter were implanted into the pedicle unilaterally.And a pilot hole was created using 3.5mm drill contralaterally on eight fresh human thoracolumbar vertebrae.Neither the screws nor the drillings penetrated the anterior cortex of the vertebral bodies.The CPC was applied to the holes and allowed to harden for 24 hours,then the pull out test was employed again.Group B:the same test as group A was employed,but pedicle screws were augmented and restored with PMMA.Group C:pedicle screws were implanted with or without CPC augmentation bilaterally,then cycli bending resistance test was employed.Group D:the same test as group C was employed,but pedicle screws were augmented with PMMA.Results:The pull out strength following CPC restoration and augmentaiton was significantly greater than that of control group ( P <0.05.Conclusion:This test demonstrates that restoration and augmentation with CPC offer a significantly increase of strength for screw fixation.
出处
《中国矫形外科杂志》
CAS
CSCD
2003年第23期1616-1618,共3页
Orthopedic Journal of China
