摘要
目的 :研究良、恶性腹水表达癌胚抗原 (CEA)的差别 ,评估检测 CEA诊断与鉴别诊断良、恶性腹水的应用价值。方法 :研究对象包括恶性腹水患者 5 2人、良性腹水患者 32人 ,采集腹水为检测标本 ,应用磁性抗体分离酶免疫测定技术 (MAIA)检测 CEA。结果 :CEA阳性表达结果在恶性腹水组为 2 9/ 5 2(5 5 .8% )、良性腹水组为 2 / 32 (6 .2 % )。检测腹水标本 CEA指标 ,诊断与鉴别诊断良、恶性腹水的特异性为 93.8%、敏感性为 5 5 .8%。结论 :良、恶性腹水表达 CEA的差别具有显著性 (P<0 .0 0 1 ) ,检测腹水标本 CEA指标诊断与鉴别诊断良。
Objective: To explore the applied value of carcinoembryonic antigen (CEA) detecting in malignant ascites diagnosing. Methods: Seventy natients were examined in the study, of them 52 cases with malignant ascites and 32 ones with benign ascites. CEA in ascites were detected by MAIA. Results: The positive results of CEA were 29/52 (55.8%) in the malignant ascites group. In the benign ascites group, the positive results of CEA were 2/32 (6.2%). In the diagnosis of malignant ascites, the specificity was 93.8% and the sensitivity was 55.8%. Conclusions: The positive results of CEA were different significantly between the malignant group and the benign group (P<0.001). CEA is a useful index for laboratory diagnosis of malignant ascites.
出处
《承德医学院学报》
2003年第4期298-299,共2页
Journal of Chengde Medical University
