摘要
目的 :探讨青年人大肠癌的发病率、临床病理特点及预后。方法 :回顾性分析 1992年至2 0 0 1年我院收治的 4 5例青年人 (≤ 30岁 )大肠癌的诊断、治疗及随访资料。结果 :临床表现主要是大便习惯改变、便血或粘液血便、腹痛。本组 4 5例病人行根治切除手术 35例 ,其中Miles术 17例 ,Dixon术 6例 ,左、右半结肠及横结肠切除术 12例 ;造瘘术 6例 ,单纯探查术 4例。癌肿好发部位为直肠和乙状结肠。病理类型多为粘液腺癌、印戒细胞癌和低分化腺癌。术后随访 4 0例 ,5年生存率为 2 7.5 %(11/ 4 0 )。结论 :青年人大肠癌临床症状不典型 ,恶性程度高 ,易误诊、漏诊 ,手术根治率和生存率低。早发现、早诊断、早治疗是提高手术根治率 ,从而提高生存率的关键。
Objective: To study the incidence, clinical features, pathological characteristics and prognosis of colorectal carcinoma in young patients. Method: Data of 45 cases treated in our hospital from 1992 to 2001 was analysed retrospectively.Results: Main clinical symptoms are changes in bowel habits, hematochezia or mucosanguineous stool and bellyache. 35 of all 45 cases were performed radical operations, including 17 miles operations, 6 Dixon operations, 12 hemicolectomies. 6 cases were performed permanent colostomy, 4 cases were performed exploratory laparotomy simply. Rectum and sigmoid colon are the common sites of colorectal carcinoma in young patients. The common pathological types are mucinous carcinoma, signet-ring cell carcinoma and low-differentiated carcinoma. 40 cases were followed up, in which the 5 years survival rate is 27.5%. Conclusion :Colorectal carcinoma in young patients has the following features: atypical clinical symptoms, higher malignant degree, being misdiagnosed and missed diagnosed easily, lower rates of radical operation and survival. Early detection, diagnosis and treatment are the key of increasing rates of radical operation and survival.
出处
《河北医学》
CAS
2003年第11期978-980,共3页
Hebei Medicine
