摘要
目的 建立本地区母婴血清总三碘甲腺原氨酸 (TT3 或T3 )、总甲状腺素 (TT4或T4)水平的正常参考值 ,为鉴定孕期甲亢或甲低及预测新生儿是否甲低提供一个生理性数据。 方法 采用放射免疫法测定 4 0例正常未孕妇女和 88对正常母婴血清T3 和T4水平。 结果 ①母血和脐血中T3 和T4水平均无性别差异 (P>0 0 5 )。②母血、脐血与正常对照组间的T3 、T4两两比较 ,除脐血与对照组的T4差异较小 (0 0 2 <P <0 0 5 )外 ,其余均有显著性差异 (P <0 0 0 1)。 结论 ①按 x ± 1 96s计算的参考值范围与按 x±t0 .0 5 ,γ·S x 计算的 95 %可信区间相差较大 ,故使用时待商讨。②妊娠期母体甲状腺激素对胎儿的影响虽有限但不可低估。
Objective To set up the normal reference serum and to supply the physiological date for distinguishing hyperthyroidism or hypothyroidism of pregnancy and detecting fetal hypothyroidism.Methods The serum levels of total T 3(TT 3 or T 3)and total T 4(TT 4 or T 4)were measured by RIA in 40 normal women and 88 couple of normal maternal-fetal.Results ①There were no sex difference of T 3 and of T 4 in maternal serum and umbilical artery (P>0 05).②There were significantly difference of T 3 and of T 4 comparision in maternal group and umbilical artery group and normal control group each other(P<0 001).besides there was smaller difference of T 3 in umbilical artery group and normal control group(0.02<P< 0.05 ).Conclusion ①There was difference in range of normal reference value at counting by means ±1.96s and ±t 0.05 ,γ·S so to be studied in practice.②T3 and T4 of maternal serum may influence growth of fetus.
出处
《医药论坛杂志》
2003年第23期3-4,共2页
Journal of Medical Forum
