摘要
目的:探讨基于中医辨证分型的祛风化痰法治疗短暂脑缺血发作的临床效果。方法:选择66例短暂脑缺血发作患者作为研究对象,按照随机数字法分为观察组和对照组两组,各33例,对照组患者给予阿司匹林治疗,观察组患者给予阿司匹林外加祛风化痰法治疗,比较两组患者治疗前后超敏C-反应蛋白(hs-CRP,C-reactive protein)、血脂水平以及颅内血流变化,比较两组患者的临床疗效。结果:两组患者治疗前LDL-C、TG、TC、hs-CRP、BA、RVA以及LVA比较差异无统计学意义(t/P=0.244/0.404、0.363/0.359、0.280/0.390、0.313/0.377、0.209/0.418、0.851/0.199、0.511/0.306、0.257/0.359),具有可比性。经过治疗,与对照组相比,观察组患者LDL-C、TG、TC、hs-CRP、RVA以及LVA值均明显降低,HDL-C水平明显升高(t/P=2.845/0.003、3.964/<0.001、2.994/0.002、7.300/<0.001、5.872/<0.001、7.368/<0.001);两组患者治疗后BA值均无显著变化(P>0.05)。观察组患者总有效率为93.94%,明显高于对照组的72.73%,差异具有统计学意义(P<0.05)。结论:祛风化痰法治疗短暂脑缺血发作可抑制血小板聚集,扩张TIA血管,改善颅内血流动力学,减轻炎症反应。
Objective:To explore the clinical effect of treatment of transient ischemic attack based on syndrome differentiation of traditional Chinese medicine.Methods:Sixty-six patients with transient ischemic attack were selected as subjects.According to the random number method,33patients in eachgroup were treated with aspirin.Patients in the observationgroup were treated with aspirin plus phlegm and blood stasis.The levels of high-sensitivity C-reactive protein(hs-CRP,C-reactive protein),blood lipids and intracranial blood flow were compared before and after treatment.The clinical efficacy of the two groups was compared.Results:There were no significant differences in LDL-C,TG,TC,hs-CRP,BA,RVA,and LVA between the observation group and the controlgroup(t/P=0.244/0.404,0.363/0.359,0.280/0.390,0.313/0.377,0.209/0.418,0.851/0.199,0.511/0.306,0.257/0.359),comparable.Compared with the controlgroup,the LDL-C,TG,TC,hs-CRP,RVA and LVA values were significantly lower in the observationgroup,and the HDL-C level was significantly increased(t/P=2.845/0.003,3.964/<0.001,2.994/0.002,7.300/<0.001,5.872/<0.001,7.368/<0.001);there was no significant change in BA values after treatment(P>0.05).The effective rate of treatment in the observationgroup was 93.94%,which was significantly higher than that in the controlgroup(72.73%),and the difference was statistically significant(t/P=0.503/0.308).Conclusion:The treatment of phlegm and blood stasis can alleviate platelet aggregation,expand TIA blood vessels,improve intracranial hemodynamics,reduce inflammation and enhance clinical treatment.
作者
李振华
Li Zhenhua(Zhengzhou Traditional Chinese Medicine Hospital,Zhengzhou 450000,China)
出处
《亚太传统医药》
2019年第4期131-134,共4页
Asia-Pacific Traditional Medicine
关键词
短暂脑缺血发作
中医辨证分型
祛风化痰法
疗效
Transient Ischemic Attack
TCM Syndrome Differentiation
Phlegm and Blood Stasis Method
Curative Effect
