期刊文献+

生物标志物对尿源性脓毒血症临床预警的研究进展 被引量:8

Research Progress of Clinical Warning about Biomarkers for Urinary Sepsis
下载PDF
导出
摘要 尿源性脓毒血症是住院患者常见的危重症,具有高发病率和死亡率。尽管近年来对尿源性脓毒血症的诊断标准进行了修订,但是仍未有金标准。在日常工作中临床医师对于如何判断和救治尿源性脓毒血症往往存在一定的认知不足。理想的生物标志物在这方面起到了很好的辅助功能。内毒素、降钙素原、可溶性CD_(14)亚型等生物标志物是现今研究较多的标志物,其在尿源性脓毒血症中起到了很好的预测作用,这些生物标志物对于尿源性脓毒血症的临床预警和预后发挥着重要的价值。 Urinary sepsis is a common critical illness in hospitalized patients with high morbidity and mortality.Although the diagnostic criteria for urinary sepsis has been revised in recent years,there is still no gold standard for the diagnosis. Clinicians often have a certain understanding insufficiency in daily work on how to judge and treat urinary sepsis.Biomarkers as a good predictor provide good assistance in this regard. Seven biomarkers such as endotoxin,procalcitonin,soluble CD14 subtype are good predictors studied more in the field,playing an important role in the clinical warning and prognosis of urinary sepsis.
作者 朱澄村 程帆 宁金卓 ZHU Chengcun;CHENG Fan;NING Jingzhuo(Department of Urology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处 《医学综述》 2019年第6期1095-1098,1104,共5页 Medical Recapitulate
基金 国家自然科学基金面上项目(81870471)
关键词 感染 尿源性脓毒血症 临床预警 生物标志物 内毒素 降钙素原 可溶性CD14亚型 Infection Urinary sepsis Clinical warning Biomarkers Endotoxin Procalcitonin Soluble CD14 subtype
  • 相关文献

参考文献7

二级参考文献88

  • 1曹礼应,谢云惠,向庆涛.慢性肾功能衰竭患者血浆肾上腺髓质素的变化[J].中国医师杂志,2004,6(12):1699-1699. 被引量:2
  • 2秦文君,贾艳焕.肾上腺髓质素和脑钠肽在充血性心力衰竭发展过程中的作用[J].山西职工医学院学报,2006,16(2):73-74. 被引量:1
  • 3姚咏明,盛志勇,林洪远,柴家科.2001年国际脓毒症定义会议关于脓毒症诊断的新标准[J].中国危重病急救医学,2006,18(11):645-645. 被引量:191
  • 4王筱璐,何莉,汤慧丽.降钙素原诊断新生儿感染性疾病的临床价值[J].中国妇幼保健,2007,22(3):426-427. 被引量:16
  • 5Levy MM,Fink MP,Marshall JC,et al.2001SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference[J] .Crit Care Med,2003,31 (4):1250-1256.
  • 6Kumar A.Optimizing antimicrobial therapy in sepsis and septic hock[J] .Crit Care Clin,2009,25(4):733-751.
  • 7Vincent JL,Moreno R,Takala J,et al.The SOFA score to describe organ dysfunction/failure[J] .Intensive Care Med,1996,22 (7):707-710.
  • 8Moretti D,Ramírez MM,Settecase CJ,et al.Usefulness of procalcitonin upon admission to intensive care in the diagnosis and prognosis of sepsis[J] .Med Intensiva,2013,37 (3):156-162.
  • 9Albanopoulos K,Alevizos L,Natoudi M,et al.C-reactive protein,white blood cells,and neutrophils as early predictors of postoperative complications in patients undergoing laparoscopic sleeve gastrectomy[J] .Surg Endosc,2013,27 (3):864-871.
  • 10Tschaikowsky K,Hedwig-Geissing M,Braun GG,et al.Predictive value of procalcitonin,interleukin-6,and c-reactive protein for surrival in postoperative patients with severe sepsis[J] .J Crit Care,2011,26(1):54-64.

共引文献106

同被引文献87

引证文献8

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部