摘要
目的:探讨周围神经侧侧缝合后神经能否再生、再生的质量以及再生神经的来源。方法:将20只实验兔随机数字表法分为两组,每组10只。左侧后肢胫神经、腓总神经为实验神经,切断腓总神经:A组腓总神经断端以远1.5cm处将胫神经、腓总神经相邻面的神经束、外膜切开,相对缝合束、外膜;B将腓总神经远断端与胫神经相邻面行端侧外膜缝合。术后12周腓总神经远端注入辣根过氧化物酶逆行示踪,行形态学和组织学检测。结果:术后12周两组神经缝合后神经均再生,再生质量无显著差异。结论:周围神经侧侧缝合后神经能够再生,再生侧支来源于胫神经,再生质量与神经端侧缝合相似。
AIM:To investigate the regeneratio n of p eripheral nerve after side-to-side neurorrhaphy and its quality and sou r ce.METHODS:Twenty rabbits were divided randoml y into Group A and Group B(n= 10).The left common peroneal nerve and t ibia nerve were exposed,and then c ommon peroneal nerve was tr ansected.In group A,the distal seg-ment of common peroneal nerve was kep t closely to neighboring tibia nerve at the site of 1. 5cm.Then epineurium an d perineurium of two neighboring segments were incised longitudinal ly for 0.5cm to expose the nerve fibers.Finally the epineurium and perineur ium of two nerves were anastomosed side-to-side.In group B,the distal segment of common peroneal nerve and neighboring tibia nerves were anast omosed with end-to-side neurorrhap hy.At 12week after operation,injected w i th horseradish peroxidases(HRP),the distal segment of common peroneal nerve was performed antidromic track-ing.The nerve regeneration was evaluated by mo rphology and histochemis try study.RESULTS:The injured nerves of two groups re ge nerated obvously after 12weeks and there was no significant di fference in the quality of regenerat ion.Peripheral nerve regeneration can b e achieved after side-to-side neurorrhaphy and its r egeneration quality is simi lar to th at of the end-to-side neurorrhaphy.
出处
《中国临床康复》
CSCD
2004年第2期270-271,T005,共3页
Chinese Journal of Clinical Rehabilitation
