摘要
目的 观察正常新生儿 β-内啡肽 (β -EP)的动态变化及其影响因素。 方法 选择正常新生儿 2 0例在新生儿期不同时间点(出生时及生后 7,1 5 ,2 8d)进行 β -EP水平的检测 ,并对几项主要影响因素 :性别、体重、胎龄、孕次、产次、生产方式及血气分析指标等进行多重回归分析。结果 正常新生儿 β -EP出生时为 (2 0 1 .45± 82 .97)ng/L ,生后 7,1 5 ,2 8d分别为 (1 71 .46± 66 .84)、(1 60 .2 3±62 .32 )、(1 52 .65± 57.41 )ng/L。除前两次之间差异有显著性外 (P <0 .0 5) ,其他各次间差异均无显著性 (P >0 .0 5) ,且性别、体重、胎龄、孕次、产次、生产方式及血气分析指标等均对 β-EP无明显影响 (P >0 .0 5)。 结论 正常新生儿在出生后 β -EP处于较高水平 ,之后逐步降低 ,约生后 1周降至较低水平并保持这一水平 ,未发现性别、体重、胎龄、孕次、产次、生产方式及血气分析指标等对 β -EP有明显影响。
Objective To observe the dynamic changes of β-endorphin(β-EP) and its influencial factors in normal newborns. Methods 20 newborns were detected β-EP levels in different time points. Multiple regression were performed in several principal influencial factors such as sex, body weight, gestational age, pregnancy outcome, birth outcome, delivery model and blood gas analysis, et al(P>0.05). Results β-EPs in newborns were (201.45±82.97)ng/L at birth,(171.46±66.84)ng/L,(160.23±62.32)ng/L,(152.65±57.41)ng/L at 7,15,24 days after birth. There were no significances between groups except the first two groups. All the principal influencial factors had no significant influence toβ-EP levels. Conclusion β-EP levels of newborns are higher at birth, and then gradually decrease to a lower level one week after birth and maintain it. The principal influencial factors have no significant influence to β-EP levels such as sex, body weight, gestational age, pregnancy outcome, birth outcome, delivery model and blood gas analysis, et al.
出处
《中国煤炭工业医学杂志》
2004年第1期6-7,共2页
Chinese Journal of Coal Industry Medicine
