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C-反应蛋白与2型糖尿病大血管病变的相关性研究 被引量:30

The association between C-reactive protein and type 2 diabetic macrovascular complication
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摘要 目的 探讨 C-反应蛋白 (CRP)与糖尿病大血管病变发生的关系。 方法 用 EL ISA方法测定 2型糖尿病 (T2 DM)患者、无糖尿病的大血管病变患者以及正常对照组的 CRP水平变化。 结果  T2 DM伴有或不伴有大血管并发症患者以及无糖尿病的大血管病变患者间血清 CRP水平无显著差异 ;大血管病变患者血清 CRP水平较非大血管病变者明显增高。 结论  CRP在 T2 Objective To study the possible association between C reactive protein(CRP) and the pathogenesis of diabetes macrovascular complication. Methods The determination of CRP levels in type 2 diabetics with or without macrovascular complication, non DM patients suffering from macrovascular disease and normal controls was made by ELISA assay. Results CRP levels of type 2 diabetics with or without macrovascular complication and non DM macrovascular disease patients were elevated. There was no significant difference between CRP levels of type 2 diabetics with or without macrovascular disease and non DM macrovascular disease patients. Serum CRP level of participants with macrovascular disease was higher than that of participants without macrovascular disease. Conclusion CPR plays a role in the initiation and progression of T2DM macrovascular complication.
出处 《中国糖尿病杂志》 CAS CSCD 2003年第4期247-249,共3页 Chinese Journal of Diabetes
关键词 C-反应蛋白 2型糖尿病 大血管病变 相关性 ELISA 炎症 C Reactive protein T2DM Diabetic angiopathies
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  • 1[1]Maseri A. Inflammation, atherosclerosis, and ischemic events-exploring the hidden side of the moon. New Engl J Med,1997,336:1014-1016.
  • 2[2]Haidari M, Javadi E, Sadeghi B, et al. Evaluation of C-reactive protein, a sensitive marker of inflammation, as a risk factor for stable coronary artery disease. Clin Biochem, 2001,33:309-315.
  • 3[3]Stern MP. Diabetes and cardiovascular disease: the "common soil" hypothesis. Diabetes, 1995,44:369-374.
  • 4[4]Barzilay JI, Abraham Linn, Heckbert SR, et al. The relation of markers of inflammation to the development of glucose disorders in the elderly. Diabetes, 2001,50:2384-2388.

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