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急性脑梗死溶栓治疗研究进展 被引量:2

Research progress in thrombolytic therapy for acute cerebral infarction
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摘要 脑血管病是老年人的常见病和多发病,发病率逐年上升,且复发率较高。急性脑梗死是因为患者脑动脉急性闭塞造成的,其治疗方法很多,如改善脑循环、脑神经营养、脑细胞保护、降低纤维蛋白原、抗血小板凝集等治疗,治疗越早预后效果越好。目前溶栓治疗越来越普遍,其治疗效果受到临床医生、患者、家属的关注。但是在其治疗过程中可出现一些并发症,如颅内出血、梗死复发、再灌注损伤等情况,可不同程度地影响预后。溶栓治疗对发病时间、药物的选择、药物使用剂量、介入方法等有一定要求,这些都是影响预后的关键因素,直接影响患者将来的生活质量。本文对急性脑梗死溶栓治疗方案和预后进行了分析总结,并对药物的选择进行了阐述,供临床参考。 Cerebrovascular disease is a common and frequently-occurring disease in the elderly.The incidence of cerebrovascular disease is increasing year by year,and the recurrence rate is higher.Acute cerebral infarction is caused by acute cerebral artery occlusion in patients.There are many treatments,such as improving cerebral circulation,brain neurotrophy,brain cell protection,reducing fibrinogen and anti-platelet aggregation and so on.The earlier the treatment,the better the prognosis.At present,thrombolytic therapy is becoming more and more popular,and the therapeutic effect of thrombolytic therapy is concerned by clinicians,patients and family members.However,some complications such as intracranial hemorrhage,recurrence of infarction and reperfusion injury in the course of treament can affect the prognosis in different degrees.Thrombolytic therapy has certain requirements on onset time,drug selection,drug dosage and interventional methods,which are the key factors affecting prognosis and directly affect the quality of life of patients in the future.In this paper,thrombolytic therapy and prognosis of acute cerebral infarction were analyzed and summarized,and the choice of drugs was elaborated for clinical reference.
作者 杨春 YANG Chun(Department of Neurology,Affiliated Hospital of Nankai University(Fourth Hospital of Tianjin),Tianjin 300222,China)
出处 《中国城乡企业卫生》 2019年第6期59-61,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 急性脑梗死 溶栓 治疗机制 药物治疗 Acute cerebral infarction Thrombolysis Therapeutic mechanism Medication
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