摘要
杨梅素是杨梅等多种植物中广泛存在的黄酮类化合物,具有抗肿瘤、降血糖、调血脂、保护心血管及减轻神经损伤等多种生物学功能。近年来,杨梅素在抗菌、抗病毒、抗炎、抗氧化及免疫调节等方面的生物学活性越来越受到人们关注。对近年来国内外有关杨梅素抗感染、抗炎、免疫调节及抗氧化等生物学作用及相关分子机制的研究进展进行综述,为其新药开发提供理论基础。
Myricetin is a kind of flavonoids widely existing in Myrica rubra and many other plants. Myricetin has lots of biological functions, such as antitumor, reducing blood sugar and lipid, protecting cardiovascular system, and reducing nervous injury. In recent years, people pay more attention to the antibacterial, antiviral, anti-inflammatory, anti-oxidant, and immunosuppressive activities of myricetin. This paper reviews the literatures on the pharmacological activities of myricetin in recent years at home and abroad and focuses on its effects and molecular mechanism of anti-infective, anti-inflammatory, immunoregulatory and anti-oxidation activities, in order to provide the evidences for developing new drugs.
作者
王潞
周云英
WANG Lu;ZHOU Yun-ying(Department of Pharmacy, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China;Medical Laboratory Diagnosis Center, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China)
出处
《中草药》
CAS
CSCD
北大核心
2019年第3期778-784,共7页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金青年基金项目(81803570)
山东省自然科学基金博士基金项目(ZR2017BH093)
济南市卫计委科技发展计划项目(2017-2-01)
关键词
杨梅素
炎症
抗氧化
抗菌
抗病毒
免疫调节
myricetin
inflammation
anti-oxidant
antibiosis
antivirus
immunoregulation
