摘要
量效关系是确定中药临床用药剂量的依据,是保障中药临床用药安全、有效的关键。对近10年来有关中药量效关系的研究思路、研究现状、研究瓶颈等相关文献进行梳理、总结,并建议将谱效关系理论引入中药量效关系研究中,为推动中药量效关系进一步深入研究提供参考和借鉴。
The dose-effect relationship of Chinese materia medica(CMM)is the basis to determine the clinical dosage,as well as the key to ensure the safety and effectiveness in clinic.In this paper,the author reviews and summarizes the research ideas,research status,and research bottlenecks related to the dose-effect relationship of CMM in the past 10 years.It is suggested to introduce the theory of spectrum-effect relationship into the study of dose-effect relationship,so as to provide reference for further research on the dose-effect relationship of CMM.
作者
朱春胜
聂安政
王笑
张冰
ZHU Chun-sheng;NIE An-zheng;WANG Xiao;ZHANG Bing(The First Affiliated Hospital of Zhengzhou University,Zhengzhou450000,China;Beijing University of Chinese Medicine,Beijing100102,China)
出处
《中草药》
CAS
CSCD
北大核心
2019年第7期1708-1712,共5页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(81673618)
北京市自然科学基金项目(7162117)
关键词
中药
量效关系
临床用药剂量
效应物质
谱效关系
Chinese materia medica
dose-effect relationship
clinical dosage
effective substa
spectrum-effect relationship
