摘要
目的比较丙泊酚复合地佐辛与芬太尼应用于无痛人流术效果及对体动的影响。方法将2016年7月-2017年5月期间来医院就诊的实施无痛人流术患者240例为研究对象,随机分为3组,每组80例。D组给予丙泊酚复合地佐辛;F组给予丙泊酚复合芬太尼;C组作为对照组给予单纯丙泊酚静脉麻醉,3组术中根据具体情况给予丙泊酚追加。比较3组术中手术时间、苏醒时间及丙泊酚总量;并比较3组术后0分钟、15分钟、30分钟、1小时、3小时视觉疼痛模拟评分(VAS);统计3组患者体动、呼吸抑制等不良反应发生情况。结果 D组、F组手术时间、苏醒时间及丙泊酚总量比较差异无统计学意义(P>0.05);D组、F组苏醒时间及丙泊酚总量分别为(1.2±0.7)分钟、(136.8±14.5)毫克,(1.3±0.8)分钟、(139.6±12.1)毫克,均低于C组(2.4±0.6)分钟、(168.7±18.9)毫克(均P<0.05);D组术后0分钟、15分钟、30分钟、1小时、3小时VAS评分均低于F组及C组(均P<0.05),而F组术后0分钟、15分钟、30分钟、1小时VAS评分均低于C组(均P<0.05)。D组、F组麻黄碱及阿托品总量均低于C组,且D组低于F组(均P<0.05)。D组及F组恶心、体动、呼吸抑制及低血压发生率均低于C组(均P<0.05)。结论丙泊酚复合地佐辛与芬太尼应用于无痛人流术效果均较佳,且体动反应少,但复合地佐辛术后疼痛程度低。
Objectives To compare propofol combined with fentanyl and Dezocine painless abortion effect and influence on body movement. Methods 240 cases of aged 19 to 45 patients with voluntary painless abortion in hospital from July 2016 to May 2017 were selected as the research subjects.And were randomly divided into 3 groups with each group of 80 cases. D group were given propofol and Dezocine;F group was given propofol combined with fentanyl;C group as the control group was treated with propofol intravenous anesthesia, 3 groups were given propofol added. According to the specific situation of the 3 groups were compared operative time, recovery time and the total amount of propofol;and to compare 3 groups’ pain visual analogue scale(VAS) at 0min, 15 min, 30 min, 1H, 3h;the 3 groups were statistically analysis incidence of respiratory depression and other adverse reactions. Results The D group, F group’ operation time,recovery time and total amount of propofol had no significant difference(P>0.05);D group, F group’ recovery time and the total amount of propofol respectively(1.2±0.7) min,(136.8±14.5) mg,(1.3±0.8) min,(139.6±12.1) mg, were lower than those in group C(2.4±0.6) min,(168.7± 18.9) mg(P<0.05);D group’ VAS scores after 0min, 15 min, 30 min, 1H, 3h were lower than that of F group and C group(P<0.05), after the operation of 0min, 15 min, 30 min, 1h F group’ VAS scores were lower than those in group C(P<0.05).Ephedrine and total atropine group D, F group were lower than that of group C, and D below F group(all P<0.05). D group and F group’ nausea, body movement, respiratory depression and hypotension incidence were lower than those in group C(P<0.05). Conclusions Propofol combined with dezocine and fentanyl used in painless abortion had better effect, and body movement was less, but combined with dezocine postoperative pain degree was low.
作者
刘丹勇
王晓光
黄晓雷
李元涛
Liu Danyong;Wang Xiaoguang;Huang Xiaolei;Li Yuantao(Department of Anesthesiology, Maternal and Child Health Hospital of Shenzhen City,518000, Guangdong Province, China)
出处
《中国病案》
2019年第1期96-99,共4页
Chinese Medical Record
关键词
丙泊酚
地佐辛
芬太尼
无痛人流术
体动
Propofol
Dezocine
Fentanyl
Painless induced abortion
Body movement
