摘要
目的探讨腹腔镜下子宫肌瘤剔除术对患者卵巢功能及血清创伤反应指标的影响。方法选取2017年5月至2018年5月间新疆医科大学第五附属医院收治的100例子宫肌瘤患者,采用奇偶数分组法分为观察组和对照组,每组50例。观察组患者采用腹腔镜下子宫肌瘤剔除术治疗,对照组患者采用传统手术治疗,比较两组患者的促黄体素、促卵泡刺激素、雌二醇、环磷酰胺、血清缺血修饰清蛋白、肌红蛋白、前列腺素E2、白细胞介素-6和心肌细胞P物质。结果治疗后,观察组患者促黄体素(17. 22±1. 35) U/L、促卵泡刺激素(20. 35±1. 24) U/L、雌二醇(224. 69±8. 53)pmol/L、环磷酰胺(8. 42±1. 33) k U/L、血清缺血修饰清蛋白(65. 33±3. 18) U/L、肌红蛋白(22. 19±1. 43) ng/ml、前列腺素E2(115. 28±8. 45) pg/ml、白细胞介素-6(6. 18±1. 28) pg/ml和心肌细胞P物质(4. 27±1. 35)μg/ml,均优于对照组的(22. 41±1. 67) U/L、(22. 44±2. 61) U/L、(254. 17±8. 12)pmol/L、(13. 17±1. 85) kU/L、(70. 42±4. 22) U/L、(26. 37±2. 55) ng/ml、(155. 56±9. 85) pg/ml、(7. 59±1. 53) pg/ml和(5. 86±1. 42)μg/ml,差异均有统计学意义(均P <0. 05)。结论对子宫肌瘤患者采用腹腔镜下子宫肌瘤剔除术治疗效果明显,可改善卵巢功能。
Objective To explore the effect of laparoscopic hysteromyomectomy on ovarian function and serum trauma response. Methods From May 2017 to May 2018,100 patients with uterine leiomyoma treated at Fifth Affiliated Hospital of Xinjiang Medical University were selected and divided into an observation group and a control group with 50 patients in each group. The observation group was treated with laparoscopic hysteromyomectom and the control group was treated with traditional surgical treatment. Luteinizing hormone,follicle-stimulating hormone,estradiol,cyclophosphamide,serum ischemic modified albumin,myohemoglobin,prostaglandin E2,interleukin-6 and substance P in cardiac myocytes were compared between the two groups. Results After the treatment,lutein( 17. 22 ± 1. 35) U/L,follicle stimulating hormone( 20. 35 ± 1. 24) U/L,estradiol( 224. 69 ± 8. 53) pmol/L,cyclophosphamide( 8. 42 ± 1. 33) k U/L,serum ischemia modified albumin( 65. 33 ± 3. 18) U/L,myoglobin( 22. 19 ± 1. 43) ng/ml,prostaglandin E2( 115. 28 ± 8. 45) pg/ml,interleukin-6( 6. 18 ± 1. 28) pg/ml and substance P in cardiac myocytes( 4. 27 ±1. 35) μg/ml in the observation group were superior to( 22. 41 ± 1. 67) U/L,( 22. 44 ± 2. 61) U/L,( 254. 17 ± 8. 12) pmol/L,( 13. 17 ± 1. 85) k U/L,( 70. 42 ± 4. 22) U/L,( 26. 37 ± 2. 55) ng/ml,( 155. 56 ± 9. 85) pg/ml,( 7. 59 ± 1. 53) pg/ml and( 5. 86 ± 1. 42) μg/ml in the control group( all P <0. 05). Conclusion Laparoscopic hysteromyomectomy can improve ovarian function in patients with uterine leiomyoma with obvious efficacy.
作者
刘雁林
陈海燕
王沛靓
沈艳丽
冯文广
LIU Yan-lin;CHEN Hai-yan;WANG Pei-liang;SHEN Yan-li;FENG Wen-guang(Department of Gynecology,Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)
出处
《中国肿瘤临床与康复》
2019年第2期137-140,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
