摘要
目的探讨肺癌患者术后并发心律失常的临床症状以及危险因素。方法选取2013年1月至2017年12月间湖北省应城市人民医院收治的219例肺癌术后患者,根据是否出现心律失常进行分组,其中79例出现心律失常的患者作为心律失常组,140例未出现心律失常的患者作为心律未失常组。整理并记录肺癌术后患者并发心律失常的临床特征,分析患者吸烟史、第一秒用力呼气量(FEV1)及FEV1/用力肺活量(FVC)等因素与肺癌患者术后心律失常的相关性。结果患者术前心电图异常、术中心包损伤、术后电解质异常以及FEV1/FVC与肺癌患者术后并发心律失常有关,差异均有统计学意义(均P <0. 05)。经Logistic多因素分析,术前心电图异常、术中心包损伤、术后电解质异常及FEV1/FVC均是肺癌患者术后并发心律失常的危险因素(均P <0. 05)。结论肺癌患者术中心包损伤、肺损伤及术后电解质紊乱是肺癌患者术后并发心律失常的独立危险因素,手术过程中应进行干预,能够降低术后心律失常的发生率。
Objective To analyze the clinical features and risk factors for postoperative arrhythmia in patients with lung cancer. Methods A total of 219 patients with lung cancer undergoing surgery at People’s Hospital of Yingcheng between January 2013 and December 2017 were selected. According to arrhythmia status,patients were divided into an arrhythmia group( 79 patients) and a non-arrhythmia group( 140 patients). The clinical features of arrhythmia complications after lung cancer were collected and recorded to analyze the relationship between the arrhythmia after lung cancer surgery and smoking history,forced expiratory volume in one second( FEV1) as well as FEV1/forced vital capacity( FVC). Results Preoperative ECG abnormalities,intraoperative pericardium injury,postoperative electrolyte abnormalities,and FEV1/FVC were associated with postoperative arrhythmia( all P < 0. 05). After Logistic multivariate analysis,preoperative ECG abnormalities,intraoperative pericardium injury,postoperative electrolyte abnormalities,and FEV1/FVC were risk factors for arrhythmia complication after lung cancer( all P < 0. 05). Conclusion Intraoperative pericardium injury,lung injury and postoperative electrolyte imbalance are the independent risk factors for arrhythmia after lung cancer. Intraoperative intervention for the above factors can reduce the incidence of postoperative arrhythmia.
作者
何文俊
张仲道
赵思鸿
HE Wen-jun;ZHANG Zhong-dao;ZHAO Si-hong(Department of Cardiovascular Medicine,People's Hospital of Yingcheng,Yingcheng 432400,China)
出处
《中国肿瘤临床与康复》
2019年第3期304-306,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
肺肿瘤
心律失常
临床特征
危险因素分析
Lung neoplasms
Arrhythmia
Clinical features
Risk factor analysis
