摘要
目的探讨肺癌患者术后合并肺部感染的临床特点及其影响因素。方法选取2016年8月至2018年8月间青岛市市立医院东院区收治的89例肺癌手术患者,按照术后是否合并肺部感染分为肺部感染组(46例)与非肺部感染组(43例)。分析肺部感染组患者的病原菌感染情况,采用单因素及多因素Logistic回归分析,探究肺癌患者术后合并发生肺部感染的影响因素。结果46例肺部感染患者中,革兰阴性菌27例(58. 7%),革兰阳性菌16例(37. 8%),真菌3例(6. 5%)。两组患者年龄、糖尿病、侵入性操作、慢性阻塞性肺疾病、切口明显疼痛和手术时间比较,差异均有统计学意义(均P <0. 05);性别和预防性使用抗菌药比较,差异无统计学意义(P> 0. 05)。上述因素纳入多因素Logistic回归分析,高龄、切口疼痛明显、慢性阻塞性肺疾病和糖尿病为肺癌患者术后合并肺部感染的独立影响因素,差异均有统计学意义(均P <0. 05)。结论肺癌患者术后合并肺部感染时,病原菌以革兰阴性菌为主,配合积极有效的预防措施,防止术后肺部感染。
Objective To investigate and analyze the clinical features and influencing factors for postoperative pulmonary infection in patients with lung cancer.Methods A retrospective analysis of 89 patients with lung cancer admitted to East Branch,Qingdao Municipal Hospital from August 2016 to August2018 were selected and were divided into a pulmonary infection group(46 patients)and a non-pulmonary infection group(43 patients)according to postoperative pulmonary infection,Univariate and multivariate Logistic analysis was used to investigate factors influencing the risk for postoperative lung infection.Results Gram-negative bacteria wa found in 27 patients(58.7%),Gram-positive bacteria was found in 16 patients(37.8%),and fungi was found in 3 patients(6.5%).There were significant difference in age,diabetes,invasive operation,chronic obstructive pulmonary disease,obvious incision pain and operation time between the two groups(all P<0.05).The difference was not statistically significant in preventive use of antibiotics between patients of different gender(P>0.05).Incorporating the above factors into multivariate logistic regression analysis showed that advanced age,incision pain,chronic obstructive pulmonary disease,and diabetes were independent factors influencing pulmonary infection after lung cancer surgery(all P<0.05).Conclusion When postoperative pulmonary infection occurred,clinicians should focus on the control of Gram-negative bacteria by antibiotics,and active and effective preventive measures should be taken to prevent postoperative pulmonary infection.
作者
耿秀丽
李艳梅
王樱洁
GENG Xiu-li;LI Yan-mei;WANG Ying-jie(Emergency Department,East Branch,Qingdao Municipal Hospital,Qingdao266000,China;Electrocardiography Room,East Branch,Qingdao Municipal Hospital,Qingdao266000,China)
出处
《中国肿瘤临床与康复》
2019年第9期1054-1057,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
肺肿瘤
手术
肺部感染
临床特点
影响因素
Lung neoplasms
Surgery
Pulmonary infection
Clinical characteristics
Influencing factors
