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晚期非小细胞肺癌患者化疗前后D-二聚体、CEA联合检测的临床意义 被引量:1

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摘要 目的检测晚期非小细胞肺癌(NSCLC)患者化疗前后血浆D-二聚体及CEA变化水平,探讨其对判断患者预后的临床意义。方法分别测定65例晚期NSCLC患者化疗前后血浆D-二聚体与CEA水平变化。结果Ⅳ期非小细胞肺癌患者的血浆D-二聚体与CEA水平均高于Ⅲ期,差别有统计学意义;肺癌化疗后CR、PR、SD组患者的血浆D-二聚体水平与化疗前相比无明显差异;肺癌化疗后病情进展患者的血浆D-二聚体水平明显升高(t=2.16,P【0.05);肺癌化疗后CR、PR组患者的CEA水平明显降低,PD组患者的CEA显著升高。结论晚期NSCLC患者化疗前后CEA含量的变化可有助于评价疗效,联合D-二聚体检测可有助于早期发现疾病进展,对评估患者预后有一定的临床意义。
出处 《中国保健营养(下半月)》 2012年第7期2484-2485,共2页 China Health Care & Nutrition
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