摘要
目的分析坎地沙坦酯对高血压合并高尿酸血症患者的尿微量蛋白排泄影响。方法选取86例符合研究标准的高血压合并高尿酸血症患者作为案例进行对比研究。两组患者均在研究开始之前1周停用降压药物。常规组每天清晨口服左旋氨氯地平进行治疗,实验组每天清晨口服坎地沙坦酯进行治疗。总结并对比两组患者的治疗效果。结果治疗后实验组患者的SBP、DBP均优于常规组患者(P<0.05);治疗后,实验组患者多项尿微量蛋白值、血清肌酐数据均显著优于常规组,差异显著,具备统计学意义(P<0.05)。结论高血压合并高尿酸血症患者采用坎地沙坦酯的临床疗效突出,可以有效的改善尿微量蛋白排泄状况,能够有效的降压并控制尿微量蛋白排泄量,维护患者肾功能,提高患者康复效益,值得在临床中推广。
Objective To analyze the effect of candesartan ester on urinary microalbumin excretion in patientswith hypertension and hyperuricemia. Methods Eighty-six hypertensive patients with hyperuricemia were selectedand compared. The two groups stopped antihypertensive drugs 1 weeks before the start of the study. The routinegroup was given levoamlodipine every morning,,and the experimental group was given candesartan ester everymorning. The therapeutic effects of the two groups were summarized and compared. Results After treatment, the SBPand DBP of the experimental group were better than those of the conventional group(P<0.05). After treatment, the dataof Urinary Microprotein and serum creatinine in the experimental group were significantly better than those in theconventional group, with significant difference(P<0.05). Conclusion Candesartan axetil is effective in the treatmentof hypertension complicated with hyperuricemia. It can effectively improve the excretion of urinary microalbumin,reduce blood pressure and control the excretion of urinary microalbumin, maintain the renal function and improve therehabilitation benefit of patients. It is worth popularizing in clinic.
作者
李宪江
谭运新
LI Xian-jiang;TAN Yun-xin(Pukou Hospital of Nanjing,Nanjing,Jiangsu 210031)
出处
《智慧健康》
2018年第35期143-144,共2页
Smart Healthcare
关键词
坎地沙坦酯
高血压
高尿酸血症
尿微量蛋白
排泄影响
Candesartan ester
Hypertension
Hyperuricemia
Urinary microalbumin
Excretory effect
