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高级别宫颈上皮内瘤变的临床诊治分析 被引量:1

Clinical Diagnosis and Treatment of High Grade Cervical Intraepithelial Neoplasia
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摘要 目的对宫颈环形电切术(LEEP)应用于高级别宫颈上皮内瘤变诊断及治疗过程中的临床意义进行研究与分析。方法回顾性分析43例高级别宫颈上皮内瘤变患者的临床资料,观察全部患者接受宫颈环形电切术前后的疾病病理分级转化情况、并发症发生情况及复发情况。结果手术前病理诊断结果为CINⅡ的12例患者中有83.33%(10/12)于手术后仍为CINⅡ,8.33%(1/12)手术后升级为CINⅢ,8.33%(1/12)手术后升级为宫颈癌;手术前病理诊断结果为CINⅢ的31例患者中有83.87%(26/31)于手术后仍为CINⅢ,9.68%(3/31)手术后降级为CINⅡ,6.45(2/31)手术后升级为宫颈癌;全部患者中仅2.33%(1/43)患者出现阴道流血增多的术后并发症;93.02%(40/43)患者疾病治愈,6.98%(3/40)患者存在手术残留,2.33%(1/43)患者于手术后1年疾病复发。结论宫颈环形电切术对高级别宫颈上皮内瘤变具有显著治疗效果,具有一定安全性,患者疾病复发率较低。 Objective To study and analyze the clinical significance of cervical ring electrotomy(LEEP) in the diagnosis and treatment of high-grade cervical intraepithelial neoplasia. Methods The clinical data of 43 patients with high-grade cervical intraepithelial neoplasia were retrospectively analyzed. All patients underwent pathological grade conversion, complications and recurrence before and after cervical ring electrosurgery. Results 83.33%(10/12) of the 12 patients with CINII before surgery were still CINII after surgery, 8.33%(1/12) were upgraded to CINIII after surgery, and 8.33%(1/12) after surgery upgrade to cervical cancer. Of the 31 patients with CINIII before surgery, 83.87%(26/31) were still CINIII after surgery, 9.68%(3/31) were postgraded to CINII after surgery, and 6.45(2/31) were upgraded to cervical cancer;only 2.33%(1/43) of all patients had postoperative complications of vaginal bleeding;93.02%(40/43) patients were cured, and 6.98%(3/40) patients had surgical residuals, 2.33%(1/43) patients relapsed 1 year after surgery. Conclusion Cervical ring electrotomy has a significant therapeutic effect on high-grade cervical intraepithelial neoplasia, and it has certain safety. The patient’s disease recurrence rate is low.
作者 卞玉娟 BIAN Yu-juan(Haimen Fifth People's Hospital,Haimen,Jiangsu 226100)
出处 《智慧健康》 2019年第3期139-140,共2页 Smart Healthcare
关键词 宫颈环形电切术 高级别宫颈上皮内瘤变 诊治 Cervical ring electrotomy High-grade cervical intraepithelial neoplasia Diagnosis and treatment
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