摘要
目的探析小剂量罗红霉素联合氨茶碱在支气管扩张治疗中的应用效果及其安全性。方法根据入院单号、双号将2016年1月至2018年12月本院接收的100例支气管扩张患者平均分为两组,每组50例,对照组实施单一的小剂量罗红霉素治疗,研究组则接受小剂量罗红霉素联合氨茶碱治疗,统计每组治疗前后肺功能及不良反应发生率。结果在FEV1/FVC及FEV1方面,治疗前,两组比较,差异无统计学意义(P>0.05);治疗后,研究组均较对照组更高,差异有统计学意义(P<0.05);在不良反应发生率方面,研究组是8.00%,对照组是10.00%,两组比较,差异无统计学意义(P>0.05)。结论支气管扩张疾病治疗过程中,小剂量罗红霉素联合氨茶碱具有显著应用效果,不仅可以减轻临床病症,增强肺功能,同时具有较高的安全性,值得推广并采纳。
Objective To investigate the effect and safety of low-dose roxithromycin combined with aminophylline in the treatment of bronchiectasis.Methods According to the admission number and the double number,100 patients with bronchiectasis received from our hospital from January to February 2018 were divided into two groups,50 in each group.The control group received a single low-dose roxithromycin treatment.The study group received low-dose roxithromycin combined with aminophylline,and the incidence of lung function and adverse reactions before and after treatment were counted.Results In terms of FEV1/FVC and FEV1,there was no significant difference between the two groups before treatment(P>0.05).After treatment,the study group was higher than the control group,the difference was statistically significant(P<0.05).In the incidence of adverse reactions,the study group was 8.00%,and the control group was 10.00%.There was no significant difference between the two groups(P>0.05).Conclusion In the treatment of bronchiectasis,low-dose roxithromycin combined with aminophylline has significant application effects,which can not only alleviate clinical symptoms,enhance lung function,but also have high safety,which is worthy of promotion and adoption.
作者
郭松文
GUO Song-wen(Department of Respiratory Medicine,Hengyang Central Hospital,Hengyang,Hunan 421000)
出处
《智慧健康》
2019年第22期138-139,146,共3页
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