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急性早幼粒细胞白血病出血机制 被引量：4

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摘要 急性早幼粒细胞白血病(APL)由于伴有严重的凝血功能障碍,常常引发致命性出血,早期死亡率极高,尤其见于APL患者化疗后骨髓抑制期。出血以不同形式发生于不同部位。研究〔1〕对APL患者接受全反式维甲酸(ATRA)和伊达比星治疗期间发生致命性出血部位的统计发现,颅内出血是出血性死亡最主要原因,并且致命性出血通常发生在诱导治疗的早期。APL患者并发出血,与APL病期与患者年龄有一定的相关性,
作者 韩丹壘 郭静明
机构地区 三峡大学第一临床医学院血液内科
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第14期4101-4103,共3页 Chinese Journal of Gerontology
关键词 白血病 急性早幼粒细胞性 出血
分类号 R733.71 [医药卫生—肿瘤]
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参考文献9

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二级参考文献11

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二级引证文献16

中国老年学杂志
2014年 第14期

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