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儿童C3肾小球病的治疗进展

Treatment progress of C3 glomerulopathy
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摘要 C3肾小球病是一种罕见的肾脏疾病,发病率为百万分之一至百万分之二,男女比例大致相等,平均发病年龄21岁,儿童占40%,临床表现可有镜下或肉眼血尿、不同程度的蛋白尿、轻-重度的高血压,一过性或持续的肾功能损害、血清补体C3降低。C3肾小球病缺乏特异性治疗。本综述主要介绍儿童C3肾小球病的治疗进展。 C3 glomerulopathies are rare forms of glomerulonephritis which are estimated to affect only one to two people per one million, and there are no difference between male and female in incidence rate. The average age of onset is 21 years old, children accounted for 40%. All patients with C3 glomerulopathies have macroscopic or gross hematuria, variable degree of proteinuria, mild to severe hypertension, transient or persistent kidney injury and low serum C3 level. There are no recognized therapeutic decisions. The progress of treatment was discussed in this topic.
出处 《中华临床医师杂志(电子版)》 CAS 2017年第2期306-309,共4页 Chinese Journal of Clinicians(Electronic Edition)
基金 吉林省发展和改革委员会 儿童急性肾损伤的临床试验研究(201005)
关键词 C3肾小球病 儿童 治疗 依库珠单抗 C3 glomerulopathy Children Treatment Eculizumab
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