摘要
胰腺癌干细胞在胰腺癌的发生、发展、转移及治疗抗性与复发中起着重要作用,但是其中的调节机制仍不清楚。深入研究特定微小RNA调控胰腺癌干细胞的作用,对于阐明胰腺癌发生发展的关键机制具有重要意义,同时有望为胰腺癌的诊治提供新的靶点。
Pancreatic cancer stem cells play an important role in the occurrence,development and metastasis as well as the therapeutic resistance and recurrence of pancreatic cancer,but the regulatory mechanisms involved are still unclear.In-depth study of the role of specific micro RNA in the regulation of pancreatic cancer stem cells is of great significance for elucidating the key mechanisms of pathogenesis of pancreatic cancer,and is expected to provide a new target for the diagnosis and treatment of pancreatic cancer.
作者
洪乐
肖卫东
HONG Le;XIAO Weidong(Department of General Surgery,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China)
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2019年第9期1137-1142,共6页
China Journal of General Surgery
基金
国家自然科学基金资助项目（81660401,81860418）
南昌大学研究生创新专项资金资助项目（CX2018184）
