摘要
目的 :探讨鼠神经生长因子穴位注射治疗小儿脑损伤后听、视力障碍的临床疗效。方法 :选择本院儿童康复中心2013年1月-2016年1月收治的脑损伤后听、视力障碍患儿96例,年龄为1个月~5岁。随机分为观察组和对照组,各48例。观察组和对照组均进行康复训练治疗。观察组给予鼠神经生长因子穴位注射,5 m L注射器抽取0.9%氯化钠注射液配鼠神经生长因子(2 m L溶解30μg),每个穴位0.2~0.3 m L;对照组给予鼠神经生长因子肌内注射(30μg,qd),观察两组患儿的疗效。结果 :观察组患儿住院时间显著低于对照组患儿(P<0.05),视力恢复正常眼数和听力恢复至正常耳数均显著高于对照组患儿(P<0.05),治疗费用略高于对照组患儿,差异无统计学意义(P>0.05)。观察组视力障碍治疗总有效率83.34%明显高于对照组总有效率70.83%(P<0.05),观察组听力障碍治疗总有效率85.42%明显高于对照组总有效率66.67%(P<0.05)。结论:鼠神经生长因子穴位注射治疗小儿脑损伤后听、视力障碍有明显的疗效,值得临床推广使用。
Objective:To investigate the clinical effect of acupoint injection of mouse nerve growth factor in the treatment of hearing and visual impairment after brain injury in children. Method:96 cases of hearing and visual impairment after brain injury patients were selected and randomly divided into the treatment group and the control group, 48 cases in each group. The observation group and the control group were all treated with rehabilitation training. The observation group was given acupoint injection of mouse nerve growth factor. 30 μg nerve growth factor was dissolved in 2 m L 0.9% sodium chloride injection, and 5 m L injector was used to extract and inject, each point of 0.2~0.3 m L; the control group was given intramuscular injection of mouse nerve growth factor(30 μg, qd). The curative effect of two groups was observed. Result:The hospitalization time of observation group was significantly lower than that of the control group(P<0.05), the number of eyes returned to normal eyesight and hearing returned to normal hearing were significantly higher than those of the control group(P<0.05), the cost of observation group was slightly higher than that of the control group, the difference was not statistically significant(P>0.05). The total effective rate of hearing impairment of observation group was 83.34% which was significantly higher than 70.83% of the control group(P<0.05), the total effective rateof hearing impairment of observation group was 85.42% which was significantly higher than 66.67% of the control group(P<0.05). Conclusion:Acupoint injection of mouse nerve growth factor has obvious curative effect on hearing and visual impairment after brain injury in children, and is worthy of clinical application.
出处
《中国执业药师》
CAS
2017年第8期24-26,30,共4页
China Licensed Pharmacist
关键词
鼠神经生长因子
穴位注射
脑损伤
听力障碍
视力障碍
Mouse Nerve Growth Factor
Acupoint Injection
Brain Injury
Hearing Impairment
Visual Disturbance
