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重组水蛭素的表达纯化及活性检测方法进展 被引量：1

Progress in the Expression, Purification and Assay of Recombinant Hirudin
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摘要 作为直接凝血酶抑制剂 ,重组水蛭素在临床上的应用已越来越重要。文章综述了重组水蛭素的表达、分离纯化及其理化性质和活性检测方法的进展。 As a direct thrombin inhibitor, recombinant hirudin(r-hirudin) has played an important role in clinical use. The progress in the expression, isolation and purification of r-hirudin are reviewed, and the physicochemical properties and the assays of r-hirudin are also introduced.
作者 陈桂良 陈钢
机构地区 上海市药品检验所
出处 《药物生物技术》 CAS CSCD 2004年第1期52-55,共4页 Pharmaceutical Biotechnology
关键词 重组水蛭素 表达 纯化 活性检测 Recombinant hirudin, Expression, Purification, Assay
分类号 Q55 [生物学—生物化学]
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参考文献29

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药物生物技术
2004年 第1期

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