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神经酰胺的合成及其细胞效应 被引量：1

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摘要 神经酰胺是在中性或酸性鞘磷脂酶的作用下由鞘磷脂产生 ,或者是由神经酰胺合成酶催化通过从头合成途径而得。神经酰胺作为第二信使 ,在细胞分化、增殖。
作者 周文 王小华 余争平
机构地区 第三军医大学大坪医院野战外科研究所核医学科 第三军医大学预防系
出处 《国外医学（临床生物化学与检验学分册）》 2004年第1期86-88,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
关键词 神经酰胺 合成 细胞效应 酸性鞘磷脂酶 中性鞘磷脂酶 细胞凋亡
分类号 R341 [医药卫生—基础医学]
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参考文献15

  • 1Gouaze V,Levade T,Andrieu-Abadie N,et al.Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells.Mol Pharmacol,2001,60(3):488-496.
  • 2Van Hoof C,Merlevede W,Goris J,et al.The Saccharomyces cerevisiae homologue YPA1 of the mammalian phosphotyrosyl phosphatase activator of protein phosphatase 2A controls progression through the G1 phase of the yeast cell cycle.J Mol Biol,2000,302(1):103-1
  • 3Marathe S,Miranda SR,Tabas I,et al.Creation of a mouse model for non-neurological (type B) Niemann-Pick disease by stable,low level expression of lysosomal sphingomyelinase in the absence of secretory sphingomyelinase:relationship between brain intra-lyso
  • 4Reagan JW Jr,Hubbert ML,Shelness GS.Posttranslational regulation of acid sphingomyelinase in niemann-pick type C1 fibroblasts and free cholesterol-enriched Chinese hamster ovary cells.J Biol Chem,2000,275(48):38104-38110.
  • 5Min JK,Yoo HS,Lee YM,et al.Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase.Anal Biochem,2002,303(2):167-175.
  • 6Jaffrezou JP,Laurent G,Levade T.Ceramide in regulation of apoptosis.Implication in multitoxicant resistance.Subcell Biochem,2002,36:269-284.
  • 7Merrill AH Jr,Sullards MC,Wang E,et al.Sphingolipid metabolism:roles in signal transduction and disruption by fumonisins.Environ Health Perspect,2001,109(suppl 2):283-289.
  • 8Nunez G,Benedict MA,Inohara N.Caspases:the proteases of the apoptotic pathway.Oncogene,1998,17(25):3237-3245.
  • 9Prieschl EE,Baumruker T.Sphingolipids:second messengers,mediators and raft constituents in signaling.Immunol Today,2000,21(11):555-560.
  • 10Lanterman MM,Saba JD.Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants.Biochem J,1998,332(2):525-531.

同被引文献19

  • 1Kim S.Y,Choi Y.H,Huh H,et al.New Antlhepatotoxic Ceremide from Lycium Chinense Fruit[J].Nat.Prod.,1997,60(03):274-276.
  • 2Jung J.H,Lee CO,Kim Y.C,et al.New Bioaitive Ceremide from Ariscema Amurense[J].Nat.Prod.,1996,59(03):319-322.
  • 3IWAO O.Organotin Antifouling Paints and Their Alternatives[J].Applied Organometallic Chemistry,2003(172):81-105.
  • 4Comez Munoz A.Modulation of Cell Signaling by Ceramides.BiochemBiophys Acta,1998(1 391):92-109.
  • 5Hannun YA.The Sphingomyelin Cycle and the Second Messenger Function of Ceramide.J.Biol.Chem.,1994(269):3 125-3 128.
  • 6Bose R,Verheij M,Haimovitz FriedmanA,et al.Ceramide Synthase Mediates Daunorubicin Induced Apoptosis:An Alternative Mechanism for Generating Death Signals.Cell,1995(82):405-414.
  • 7Haimovitz Friedman A,Kolesnick RN,Fuks Z.Ceramide Signaling in Apoptosis.Br.Med.Bull.,1997(53):539-553.
  • 8Kolesnick RN,Haimovitz Friedman A,Fuks Z.The Sphingomyelin Signal Transduction Pathway Mediates Apoptosis for Tumor Necrosis Factor,Fas and Ionizing Radiation.Biochem.Cell Biol.,1994(72):471.
  • 9Eun HA,Joseph JS.Sphingoid Bases and Ceramide Induce Apoptosis in HT229 and HCT2116 Human Colon Cancer Cells.Exp.Biol.Med.,2002(227):345-353.
  • 10Van Curp M,Festjens N,Van Loo C,et al.Mitochondrial Intermembrane Proteins in Cell Death.Biochem.Biophy.Res.Commun,2003(304):487-497.

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国外医学（临床生物化学与检验学分册）
2004年 第1期

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