摘要
目的 探讨前列腺癌集团检诊对临床前列腺癌诊断的影响。 方法 总结 1996至2 0 0 1年集团检诊发现的 67例前列腺癌和 1986至 2 0 0 1年长春各大医院诊治的 3 58例前列腺癌患者资料 ,从年度及年龄分布、临床分期、血清前列腺特异性抗原 (PSA)含量、病理分级和治疗等方面进行对比分析。 结果 1999至 2 0 0 1年 3年间年均确诊例数较 1986至 1989年增长 4.7倍。其中集团组B期以下早期癌占 58.2 % ,临床组只占 2 7.9% ,且多为偶发癌 ;转移癌的诊断率集团组低于临床组 ;临床组PSA≥ 2 0ng/ml的比率高于集团组 ,低分化癌的比率高于集团组 ,差异均有统计学意义。集团组行前列腺癌根治术的比率较临床组提高了 15.3 %。 结论 集团检诊可以真正揭示国人前列腺癌的发病现状 ,可明显增加临床前列腺癌特别是早期癌的诊断例数 。
Objective To investigate the influence of t he mass screening on the diagnostic status of the conventional ordinary prostati c cancer (CaP). Methods Sixty seven cases of prostate ca ncer detected by mass screening (January 1996～December 2001) and 358 cases diag n osed at the outpatient of various hospitals in Changchun (January 1986～December 2001) were compared in terms of age distribution,clinical stages,level of serum prostate special antigen(PSA),pathological grade and treatment modalities,with a SPSS analysis system. Results The annual average incide nce of CaP during 1999 to 2001 increased 4.72 times when compared to the 1986 to 1989’s.In the screening group,the cases with clinical stage A and B accounted for 58.2%. In the clinical group, it was only 27.9%,and mostly detected incident ally.Furthermore,in the screening group the percentage of the cases beyond 20 ng /ml PSA and of poorly differentiated carcinoma were much lower compared to the c linical group.These differences were statistically significant.The cases of radi cal prostatectomy in the screening group increased 15.3% compared with that of t he clinical group. Conclusions Only the mass screening c an really reveal the actual prevalence of prostate cancer.It can markedly raise the number of prostate cancer,especially the cancer in the early stage.The mass screening is inevitable to detect the curable early stage prostate cancer.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2004年第2期103-105,共3页
Chinese Journal of Urology
基金
中日政府间专项技术合作项目(1999)
