摘要
目的 探讨饮水中过量氟化物对女性前臂骨密度的影响 ,以寻找地方性氟中毒的快速筛选方法。方法 在地氟病区随机选择 2 0～ 66岁女性居民 80名 ,在城区选择 71名女性居民作对照组 ,测定尿氟 ,用SPA测定骨密度。比较两组骨密度的差异和骨质疏松的检出率。结果 与对照组比较 ,在不同的年龄组 ,地氟病区女性居民前臂骨密度平均值的显著性差异表现不一致 ,无明显规律可循。但地氟病区女性骨质疏松的检出率高于对照组 (P <0 0 0 1 )。结论 饮水中过量的氟化物可使人群前臂骨密度发生变化 ,地氟病区女性骨质疏松的检出率高于正常人群 。
Objective To determine the effect of high leve l fluoride in drinking water on bone mineral density (BMD), thereby finding a meth od for screening endemic fluorosis Methods 80 female resident s in the endemic fluorosis area and 71 women in urban area were recruited randoml y as subjects and controls,respectively Fluoride concentration in urine was det er mined,and single photon absorptionetry (SPA) was used to determine the BMD of th e forearms The difference in BMD and detection rate of osteoporosis between the two groups was analyzed Results Compared with the controls, th e difference in the mean value of BMD was inconsistent in different age groups,wi thout regularity,however,the rate of osteoporosis been detected is higher in th e subjects of endemic fluorosis area than the controls (P<0 001) C onclusion High concentration of fluoride in the drinking water may resu lt in the variation of BMD in the forearm by population levels The rate of oste o porosis been detected in the female group is higher in the endemic fluorosis are a than the normal population,osteoporosis and osteosclerosis in the endemic fluo rosis area may be regarded as a screening method
出处
《中国骨质疏松杂志》
CAS
CSCD
2003年第2期141-142,110,共3页
Chinese Journal of Osteoporosis
关键词
地氟病区
女性
前臂
骨密度
骨硬化
骨质疏松症
Single Photon Absorptionetry(SPA)
Bone mineral d ensity
Osteoporosis
Osteosclerosis
Endemic fluororosis
