摘要
药物成瘾具有明显的心理成因,其中,成瘾者的人格特点,特别是感觉寻求人格特质,是导致药物成瘾的重要病原性因素。中脑边缘体多巴胺系统是感觉寻求行为与药物成瘾行为共同的脑奖赏系统,而多巴胺受体的遗传表达至少部分建立在个体执行新奇寻求和药物成瘾的行为上。感觉寻求特质对药物成瘾的作用受环境因素(父母,同伴)调节。文章也评述了感觉寻求相关研究所采用的测量工具。
Addiction is apparently affected by psychological factors. Personality factors are powerful etiologic factors in addiction, especially the sensation seeking trait. Its argued that the mesolimbic dopamine system of the brain is the same reward mechanism for the sensation seeking and drug abusing. The DNA variants of the dopamine D4 receptor gene are associated with the personality traits of sensation seeking and the behavior of drug abusing. The influence of sensation seeking on addiction is mediated by environmental factors as family and peer. The psychometric instruments employed to sensation seeking addicts are also discussed.
出处
《心理科学进展》
CSSCI
CSCD
北大核心
2004年第1期67-71,共5页
Advances in Psychological Science
