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Research progress of the endocrine disrupting activities of polychlorinated biphenyls 被引量：12

Research progress of the endocrine disrupting activities of polychlorinated biphenyls
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摘要 Polychlorinated biphenyls (PCBs) arc global persistent organic pollutants. Almost all commercial PCBs mixtures, single PCB congener, and their metabolites possess endocrine disrupting activities. They can disrupt the estrogen/androgen system, thyroid hormone system and other endocrine systems by interfering with the synthesis, transport, storage, metabolism, and feedback regulation of hormones. The newest data related to the endocrine disrupting activities of PCBs and their mechanisms arc reviewed and the research perspectives arc also discussed. Polychlorinated biphenyls (PCBs) are global persistent organic pollutants. Almost all commercial PCBs mixtures, single PCB congener, and their metabolites possess endocrine disrupting activities. They can disrupt the estro-gen/androgen system, thyroid hormone system and other endocrine systems by interfering with the synthesis, transport, storage, metabolism, and feedback regulation of hormones. The newest data related to the endocrine disrupting activities of PCBs and their mechanisms are reviewed and the research perspectives are also discussed.
作者 ZHOUJingming QINZhanfen CONGLin XUXiaobai
机构地区 ResearchCenterforEco-EnvironmentalSciences
出处 《Chinese Science Bulletin》 SCIE EI CAS 2004年第3期215-219,共5页
关键词 内分泌紊乱 多氯联苯 PCB 有机污染物 环境污染 免疫系统 polychlorinated biphenyls, endocrine disruptor, thyroid hormone disruptor, environmental estrogen.
分类号 X131 [环境科学与工程—环境科学]
  • 相关文献

参考文献11

  • 1FANG Changge,ZHANG Caigiao,QIAO Huili,XIA Guoliang,CHEN Yaoxing.Sexual difference in gonadal development of embryonic chickens after treatment of polychlorinated biphenyls[J].Chinese Science Bulletin,2001,46(22):1900-1903. 被引量：4
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二级参考文献18

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同被引文献144

引证文献12

二级引证文献59

Chinese Science Bulletin
2004年 第3期

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