摘要
目的:研究椎体骨密度、体积骨密度与生物力学强度的关系及意义。方法:取8具完整胸腰段脊柱标本,用双能X线骨密度仪测试每个椎体的骨矿含量、面积、高度。游离成单个椎体,测出每个椎体的体积,计算出体积骨密度,按骨质疏松试行诊断标准分成正常对照组、轻中度骨质疏松组和重度骨质疏松组,进行生物力学凹入实验,测试椎体静态压缩下的最大载荷和刚度。结果:正常对照组、轻中度骨质疏松组和重度骨质疏松组平均骨密度分别为(0.92±0.14),(0.59±0.10)和(0.39±0.09)g/cm2;体积骨密度分别为(0.33±0.10),(0.23±0.09)和(0.15±0.08)g/cm3,3组间的最大载荷分别为(247.923±50.811),(128.141±49.524)和(84.631±30.522)N;抗压刚度分别为(202.22±73.32),(100.33±65.21)和(80.55±15.48)N/mm。骨密度、体积骨密度与椎体最大载荷和刚度呈正相关关系。结论:椎体骨密度、体积骨密度与椎体的生物力学性质有明显的相关关系,其中体积骨密度与生物力学强度之间的相关性更好,是诊断骨质疏松症的重要指标。
AIM:To explore the relation among bone mineral density(BMD) of vertebra and volume and intensity of biomechanics, and to explore the significances. METHODS: Eight complete spine samples of chest and waist were selected.The bone mineral content(BMC),area and height of each sample were evaluated with DEXA and separated into individual vertebral bodies. The volumes of vertebral bodies were measured and the values of volume BMD were calculated. According to the diagnostic standard of osteoporosis,all vertebral bodies were divided into 3 groups: normal control group,mild to moderate osteoporosis group and serious osteoporosis group, and were conducted the indentation test. The maximum strengths and stiffness of those vertebral bodies under static compression were measured. RESULTS:In the control group, the mild to moderate osteoporosis group and the serious osteoporosis group, the average BMD were (0.92±0.14), (0.59±0.10) and (0.39±0.09) g/cm2, the average volume BMD were (0.33±0.10), (0.23±0.09) and (0.15±0.08) g/cm3,the maximum load strength were (247.923±50.811),(128.141±49.524) and(84.631± 30.522)N,the maximum stiffness were(202.22±73.32),(100.33±65.21) N/mm and (80.55±15.48)N/mm.The BMD, maximum load strength and stiffness were positively related. CONCLUSION: The biomechanic characters of vertebral body are obviously correlated with the BMD and volume BMD,the relation between volume BMD and the strength is better.The VBMD is a significant index of the diagnosis of osteoporosis.
出处
《中国临床康复》
CSCD
2004年第5期880-881,共2页
Chinese Journal of Clinical Rehabilitation
基金
广东省科技厅重点项目(99B06703G)~~
