摘要
目的:观察补肾逐瘀汤对血管性痴呆的临床疗效。方法:对82例确诊为血管性痴呆的患者分为两组(治疗组48例、对照组34例),对照组予甲磺酸二氢麦碱、胞磷胆碱治疗,治疗组加用补肾逐瘀汤。观察中医征候、简明精神状态评价量表(MMSE),日常生活活动(ADL)。结果:治疗组显效24例,有效18例,无效6例,总有效率87%;对照组显效13例,有效8例,无效13例,总有效率62%。两组总有效率有显著性差异(χ2=7.405,P<0.01)。治疗组的中医症状治疗组显效24例,有效17例,无效7例,总有效率85%;对照组显效6例,有效9例,无效19例,总有效率44%。两组总有效率差异有显著性意义(χ2=15.677,P<0.01)。治疗组、对照组均能显著改善MMSE,ADL积分,t=7.115～15.225,P<0.01,而中西医结合治疗组对MMSE和ADL能力积分的改变显著高于对照组(MMSEt=2.874,P<0.01;ADLt=2.248,P<0.05)。结论:补肾逐瘀汤能显著改善血管性痴呆患者中医症状、日常生活活动能力。
AIM:To observe the therapeutic effect of bushen zhuyu tang on vascular dementia(VD).METHODS:Eighty-two VD patients were divided into control group of 34 cases(treated with dihydroergotoxine and citicoline) and treatment group of 48 cases(the treatment above mentioned plus bushen zhuyu tang).Changes of traditional Chinese medicine(TCM) symptoms were observed,and mini-mental state examination(MMSE) and activity of daily living scale(ADL) were used to evaluate the therapeutic effects.RESULTS:In the treatment group,24 cases showed marked improvement,18 had improvement,6 were unchanged,while 13,8 and 13 respectively in the control group.The total effective rates were 87%and 62%,with statistical significance(χ2=7.405,P< 0.01).For the observation of TCM symptoms,there were 24 cases of marked improvement,17 of improvement and 7 of inefficacy in the treatment group with the 85%total effective rate,while there were 6,9 and 19 respectively in the control group with the 44%total effective rate.A significant difference was found between the two groups in the total effective rate of TCM symptoms(χ2=15.677,P< 0.01). Remarkable improvement in MMSE and ADL scores were observed in both two groups(t=7.115-15.225,P< 0.01),especially in the treatment group(MMSE:t=2.874,P< 0.01;ADL:t=2.248,P< 0.05).CONCLUSION:Bushen zhuyu tang can improve TCM symptoms and ADL of VD patients.
出处
《中国临床康复》
CSCD
2004年第7期1302-1303,共2页
Chinese Journal of Clinical Rehabilitation
